Mallotophenone

Mallotophenone
Names

IUPAC name 1-[3-[(3-acetyl-2,4-dihydroxy-6-methoxy-5-methylphenyl)methyl]-2,6-dihydroxy-4-methoxy-5-methylphenyl]ethanone
Identifiers
CAS Number	98569-63-2
3D model (JSmol)	Interactive image
ChemSpider	155882
KEGG	C10708
PubChem CID	179090
InChI InChI=1S/C21H24O8/c1-8-16(24)14(10(3)22)18(26)12(20(8)28-5)7-13-19(27)15(11(4)23)17(25)9(2)21(13)29-6/h24-27H,7H2,1-6H3 Key: JXSPGOIAWPYMGS-UHFFFAOYSA-N InChI=1/C21H24O8/c1-8-16(24)14(10(3)22)18(26)12(20(8)28-5)7-13-19(27)15(11(4)23)17(25)9(2)21(13)29-6/h24-27H,7H2,1-6H3 Key: JXSPGOIAWPYMGS-UHFFFAOYAZ
SMILES Cc1c(O)c(C(=O)C)c(O)c(c1OC)Cc(c(OC)c2C)c(O)c(C(C)=O)c2O
Properties
Chemical formula	C₂₁H₂₄O₈
Molar mass	404.41 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Mallotophenone is a dimeric phlorogucinol found in Mallotus oppositifolius or in Mallotus japonicus.

The bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of M. oppositifolius collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotophenone, together with mallotojaponins B and C. These compounds show antiproliferative and antiplasmodial activities.^[1]

References

↑ Harinantenaina, Liva; Bowman, Jessica D.; Brodie, Peggy J.; Slebodnick, Carla; Callmander, Martin W.; Rakotobe, Etienne; Randrianaivo, Richard; Rasamison, Vincent E.; Gorka, Alexander; Roepe, Paul D.; Cassera, Maria B.; Kingston, David G. I. (2013). "Antiproliferative and Antiplasmodial Dimeric Phloroglucinols fromMallotus oppositifoliusfrom the Madagascar Dry Forest(1)". Journal of Natural Products. 76 (3): 388–93. PMC 3606680 . PMID 23286240. doi:10.1021/np300750q.

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