MAB21L2

MAB21L2
Identifiers
Aliases	MAB21L2, MCOPS14, Mab-21-like 2 (C. elegans), mab-21 like 2, MCSKS14
External IDs	MGI: 1346022 HomoloGene: 7824 GeneCards: MAB21L2
Gene location (Human) Chr. Chromosome 4 (human)[1] Band No data available Start 150,581,922 bp[1] End 150,584,693 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band No data available Start 86,545,581 bp[2] End 86,548,629 bp[2]
Gene ontology Molecular function • protein binding Cellular component • nucleus Biological process • eye development • multicellular organism development • camera-type eye development • nervous system development • positive regulation of cell proliferation • embryonic body morphogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10586	23937
Ensembl	ENSG00000181541	ENSMUSG00000057777
UniProt	Q9Y586	Q8BPP1
RefSeq (mRNA)	NM_006439	NM_011839
RefSeq (protein)	NP_006430	NP_035969
Location (UCSC)	Chr 4: 150.58 – 150.58 Mb	Chr 4: 86.55 – 86.55 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.^[5]

Function

This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.