List of Schedule I drugs (US)

This is the list of Schedule I drugs as defined by the United States Controlled Substances Act.[1] The following findings are required for drugs to be placed in this schedule:[2]

  1. The drug or other substance has a high potential for abuse.
  2. The drug or other substance has no currently accepted medical use in treatment in the United States.
  3. There is a lack of accepted safety for use of the drug or other substance under medical supervision.

Except as specifically authorized, it is illegal for any person:

  1. to manufacture, distribute, or dispense, or possess with intent to manufacture, distribute, or dispense, a controlled substance; or
  2. to create, distribute, or dispense, or possess with intent to distribute or dispense, a counterfeit substance.[3]

The complete list of Schedule I drugs follows.[1] The Administrative Controlled Substances Code Number for each drug is included.

Opioids

ACSCN Drug
9815 Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl]-N-phenylacetamide)
9601 Acetylmethadol
9602 Allylprodine
9603 Alphacetylmethadol (except levo-alphacetylmethadol also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM)
9604 Alphameprodine
9605 Alphamethadol
9814 Alpha-methylfentanyl (N-[1-(alpha-methyl-beta-phenyl)ethyl-4-piperidyl] propionanilide; 1-(1-methyl-2-phenylethyl)-4-(N-propanilido) piperidine)
9832 Alpha-methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4- piperidinyl]-N-phenylpropanamide)
9606 Benzethidine
9607 Betacetylmethadol
9830 Beta-hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4- piperidinyl]-N-phenylpropanamide)
9831 Beta-hydroxy-3-methylfentanyl (other name: N-[1-(2-hydroxy-2- phenethyl)-3-methyl-4-piperidinyl]-N-phenylpropanamide
9608 Betameprodine
9609 Betamethadol
9611 Betaprodine
9612 Clonitazene
9613 Dextromoramide
9615 Diampromide
9616 Diethylthiambutene
9168 Difenoxin
9617 Dimenoxadol
9618 Dimepheptanol
9619 Dimethylthiambutene
9621 Dioxaphetyl butyrate
9622 Dipipanone
9623 Ethylmethylthiambutene
9624 Etonitazene
9625 Etoxeridine
9626 Furethidine
9627 Hydroxypethidine
9628 Ketobemidone
9629 Levomoramide
9631 Levophenacylmorphan
9813 3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-piperidyl]-N-phenylpropanamide)
9833 3-methylthiofentanyl (N-[(3-methyl-1-(2-thienyl)ethyl-4-piperidinyl]-N-phenylpropanamide)
9632 Morpheridine
9661 MPPP (1-methyl-4-phenyl-4-propionoxypiperidine)
9633 Noracymethadol
9634 Norlevorphanol
9635 Normethadone
9636 Norpipanone
9812 Para-fluorofentanyl (N-(4-fluorophenyl)-N-[1-(2-phenethyl)-4-piperidinyl] propanamide
9663 PEPAP (1-(-2-phenethyl)-4-phenyl-4-acetoxypiperidine
9637 Phenadoxone
9638 Phenampromide
9647 Phenomorphan
9641 Phenoperidine
9642 Piritramide
9643 Proheptazine
9644 Properidine
9649 Propiram
9645 Racemoramide
9835 Thiofentanyl (N-phenyl-N-[1-(2-thienyl)ethyl-4-piperidinyl]-propanamide
9750 Tilidine
9646 Trimeperidine

Opium derivatives

Heroin powder
ACSCN Drug
9319 Acetorphine
9051 Acetyldihydrocodeine
9052 Benzylmorphine
9070 Codeine methylbromide
9053 Codeine-N-Oxide
9054 Cyprenorphine
9055 Desomorphine
9145 Dihydromorphine
9335 Drotebanol
9056 Etorphine (except hydrochloride salt)
9200 Heroin (diacetylmorphine)
9301 Hydromorphinol
9302 Methyldesorphine
9304 Methyldihydromorphine
9305 Morphine methylbromide
9306 Morphine methylsulfonate
9307 Morphine-N-Oxide
9308 Myrophine
9309 Nicocodeine
9312 Nicomorphine
9313 Normorphine
9314 Pholcodine
9315 Thebacon

Hallucinogenic or psychedelic substances

ACSCN Drug
7249 Alpha-Ethyltryptamine (αET)
7391 4-bromo-2,5-dimethoxy-amphetamine (DOB)
7392 4-Bromo-2,5-dimethoxyphenethylamine (2C-B)
7396 2,5-dimethoxyamphetamine (DOA)
7399 2,5-Dimethoxy-4-ethylamphetamine (DOE)
7348 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7), its optical isomers, salts and salts of isomers
7411 4-methoxyamphetamine (PMA)
7401 5-methoxy-3,4-methylenedioxyamphetamine (MMDA)
7395 4-methyl-2,5-dimethoxyamphetamine (DOM; STP)
7400 3,4-methylenedioxyamphetamine (MDA, Sassafrass)
7405 3,4-methylenedioxymethamphetamine (MDMA, Molly)
7404 3,4-methylenedioxy-N-ethylamphetamine (MDEA; MDE)
7402 N-hydroxy-3,4-methylenedioxyamphetamine (N-hydroxy MDA)
7390 3,4,5-trimethoxyamphetamine (TMA)
7431 5-methoxy-N,N-dimethyltryptamine (5-methoxy-3-[2-(dimethylamino)ethyl]indole; 5-MeO-DMT)
7432 Alpha-methyltryptamine (αMT)
7433 Bufotenine
7434 Diethyltryptamine (DET)
7435 Dimethyltryptamine (DMT)
7439 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), its isomers, salts and salts of isomers
7260 Ibogaine
7315 Lysergic acid diethylamide (LSD)
7360 Marihuana or hemp, including cannabis resin
7350 Marihuana extracts; hemp extracts; cannabinoids[4]
7381 Mescaline
7374 Parahexyl
7415 Peyote
7482 N-ethyl-3-piperidyl benzilate
7484 N-methyl-3-piperidyl benzilate
7437 Psilocybin
7438 Psilocin
7370 Tetrahydrocannabinol (THC)
7455 Ethylamine analog of phencyclidine (Eticyclidine; PCE)
7458 Pyrrolidine analog of phencyclidine (PCPy)
7470 Thiophene analog of phencyclidine (TCP)
7473 1-[1-(2-thienyl)cyclohexyl]pyrrolidine (TCPy)
1248 4-methylmethcathinone (Mephedrone)
7535 3,4-methylenedioxypyrovalerone (MDPV)
7509 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E)
7508 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D)
7519 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C)
7518 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I)
7385 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2)
7532 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4)
7517 2-(2,5-Dimethoxyphenyl)ethanamine (2C-H)
7521 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N)
7524 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C-P)
7540 3,4-Methylenedioxy-N-methylcathinone (Methylone)

Depressants

ACSCN Drug
2010 gamma-Hydroxybutyric acid (GHB; sodium oxybate; sodium oxybutyrate) except formulations in an FDA-approved drug product are Schedule III
2572 Mecloqualone
2565 Methaqualone

Stimulants

Products containing BZP.
ACSCN Drug
1585 Aminorex (aminoxaphen; 2-amino-5-phenyl-2- oxazoline; or 4,5-dihydro-5-phenly-2-oxazolamine)
7493 N-benzylpiperazine (some other names: BZP; 1-benzylpiperazine), its optical isomers, salts and salts of isomers
1235 Cathinone
1503 Fenethylline
1237 Methcathinone (Some other names: 2-(methylamino)-propiophenone; alpha-(methylamino)propiophenone; 2-(methylamino)-1-phenylpropan-1-one; alpha-N-methylaminopropiophenone; monomethylpropion; ephedrone; N-methylcathinone; methylcathinone; AL-464; AL-422; AL-463 and UR1432), its salts, optical isomers and salts of optical isomers
1590 (+/-)cis-4-methylaminorex
1475 N-ethylamphetamine
1480 N,N-dimethylamphetamine (also known as N,N-alpha-trimethyl-benzeneethanamine; N,N-alpha-trimethylphenethylamine)

Cannabimimetic agents

ACSCN Drug
7297 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497)
7298 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog)
7118 1-pentyl-3-(1-naphthoyl)indole (JWH-018 and AM678)
7173 1-butyl-3-(1-naphthoyl)indole (JWH-073)
7019 1-hexyl-3-(1-naphthoyl)indole (JWH-019)
7200 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200)
6250 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250)
7081 1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH-081)
7122 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)
7398 1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398)
7201 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201)
7694 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM694)
7104 1-pentyl-3-[(4-methoxy)-benzoyl]indole (SR-19 and RCS-4)
7008 1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole 7008 (SR-18 and RCS-8)
7203 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203)

Temporary/emergency listings

These items are listed by the Secretary of Health and Human Services pursuant to 21 CFR 1308.49.[5][6]

ACSCN Drug
7144 (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7011 [1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (5-fluoro-UR-144, 5-F-UR-144, XLR-11, 1-(5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7048 N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts and salts of isomers (APINACA, AKB-48)
7222 Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (QUPIC, PB-22)[7]
7225 Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (5-fluoro-PB-22; 5F-PB-22)[7]
7012 N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA)[7]
7035 N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (ADB-PINACA)[7]
7031 N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (AB-CHMINACA)[8]
7023 N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA)[8]
7024 [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201)[8]
7538 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25I-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5)[9]
7537 2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82)[9]
7536 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36)[9]
9547 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]N-methylbenzamide) (U-47700)[10]
9821 Acetylfentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide)[11]
9834 N-(1-Phenethylpiperidin-4-yl)-N-phenylfuran-2-carboxamide (furanyl fentanyl)[12]
7034 2-(1-(5-Fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (5F-ADB, 5F-MDMB-PINACA)[13]
7033 Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate (5F-AMB)[13]
7049 N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48)[13]
7010 N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (ADB-FUBINACA)[13]
7042 Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-CHMICA, MMB-CHMINACA)[13]
7020 Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-FUBINACA)[13]

References

  1. 1 2 21 CFR 1308.11 (CSA Sched I) with changes through 77 FR 64032 (Oct 18, 2012). Retrieved September 6, 2013.
  2. 21 U.S.C. § 812(b)(1) United States Code via Cornell University's Legal Information Institute. Retrieved on 2007-10-02.
  3. Drug Enforcement Administration (DEA) (22 Jan 2002). "Title 21 — Food and Drugs Chapter 13 - Drug Abuse Prevention and Control Subchapter I — Control and Enforcement Part D — Offenses and Penalties: Sec. 841. Prohibited Acts A(a)". Retrieved 23 Oct 2009.
  4. https://www.gpo.gov/fdsys/pkg/FR-2016-12-14/pdf/2016-29941.pdf
  5. Code of Federal Regulations, 2012-04-01
  6. The first 8 items in the temporary section of the schedule shown on the DEA website are not included here because they are duplicates of entries in the tables above. Presumably, this is because they were made permanent and copied there at some point, but inadvertently not deleted from this temporary listing section.
  7. 1 2 3 4 "Schedules of controlled substances: temporary placement of four synthetic cannabinoids into Schedule I. Final order". Fed Regist. 79 (27): 7577–7582. Feb 10, 2014. PMID 24605391.
  8. 1 2 3 Drug Enforcement Administration, Department of Justice (2015). "Schedules of controlled substances: Temporary placement of three synthetic cannabinoids into schedule I. Final order". Federal register. 80 (20): 5042–7. PMID 25730924.
  9. 1 2 3 Drug Enforcement Administration (2015). "Schedules of Controlled Substances: Extension of Temporary Placement of Three Synthetic Phenethylamines in Schedule I. Final order". Fed Regist. 80 (219): 70657–9. PMID 26567439.
  10. "DEA Schedules Deadly Synthetic Drug U-47700". November 10, 2016.
  11. Drug Enforcement Administration (2015). "Schedules of Controlled Substances: Temporary Placement of Acetyl Fentanyl Into Schedule I. Final order". Fed Regist. 80 (137): 42381–5. PMID 26189217.
  12. Drug Enforcement Administration, Department of Justice (2016). "Schedules of Controlled Substances: Temporary Placement of Furanyl Fentanyl Into Schedule I. Final order.". Fed Regist. 81 (229): 85873–7. PMID 27906535.
  13. 1 2 3 4 5 6 "Schedules of Controlled Substances: Temporary Placement of Six Synthetic Cannabinoids (5F-ADB, 5F-AMB, 5F-APINACA, ADB-FUBINACA, MDMB-CHMICA and MDMB-FUBINACA) Into Schedule I". Drug Enforcement Administration.
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