Leucine rich repeat containing 15

LRRC15

Identifiers

LRRC15, LIB, Leucine rich repeat containing 15

External IDs

MGI: 1921738 HomoloGene: 26080 GeneCards: LRRC15

Gene location (Human)

Chr.	Chromosome 3 (human)^[1]

Band	No data available	Start	194,355,247 bp^[1]
Band	No data available	End	194,369,743 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 16 (mouse)^[2]

Band	No data available	Start	30,269,302 bp^[2]
Band	No data available	End	30,283,256 bp^[2]

Gene ontology
Molecular function	• fibronectin binding • protein kinase inhibitor activity • laminin binding • collagen binding
Cellular component	• cytoplasm • integral component of membrane • extracellular exosome • membrane
Biological process	• receptor-mediated virion attachment to host cell • negative regulation of protein kinase activity • cytokine-mediated signaling pathway • negative regulation of JAK-STAT cascade • positive regulation of cell migration • negative regulation of protein localization to plasma membrane
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


131578


74488

Ensembl


ENSG00000172061


ENSMUSG00000052316

UniProt


Q8TF66


Q80X72

RefSeq (mRNA)


NM_130830 NM_001135057


NM_028973

RefSeq (protein)


NP_001128529 NP_570843


NP_083249

Location (UCSC)

Chr 3: 194.36 – 194.37 Mb

Chr 3: 30.27 – 30.28 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Leucine rich repeat containing 15 is a protein that in humans is encoded by the LRRC15 gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172061 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052316 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Leucine rich repeat containing 15". Retrieved 2014-08-25.

Muzny, D. M.; Scherer, S. E.; Kaul, R.; Wang, J.; Yu, J.; Sudbrak, R.; Buhay, C. J.; Chen, R.; Cree, A.; Ding, Y.; Dugan-Rocha, S.; Gill, R.; Gunaratne, P.; Harris, R. A.; Hawes, A. C.; Hernandez, J.; Hodgson, A. V.; Hume, J.; Jackson, A.; Khan, Z. M.; Kovar-Smith, C.; Lewis, L. R.; Lozado, R. J.; Metzker, M. L.; Milosavljevic, A.; Miner, G. R.; Morgan, M. B.; Nazareth, L. V.; Scott, G.; Sodergren, E. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–1198. PMID 16641997. doi:10.1038/nature04728.
Reynolds, P. A.; Smolen, G. A.; Palmer, R. E.; Sgroi, D; Yajnik, V; Gerald, W. L.; Haber, D. A. (2003). "Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein". Genes & Development. 17 (17): 2094–107. PMC 196452 . PMID 12923058. doi:10.1101/gad.1110703.
O'Prey, J; Wilkinson, S; Ryan, K. M. (2008). "Tumor antigen LRRC15 impedes adenoviral infection: Implications for virus-based cancer therapy". Journal of Virology. 82 (12): 5933–9. PMC 2395123 . PMID 18385238. doi:10.1128/JVI.02273-07.
Satoh, K; Hata, M; Yokota, H (2002). "A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid". Biochemical and Biophysical Research Communications. 290 (2): 756–62. PMID 11785964. doi:10.1006/bbrc.2001.6272.
Satoh, K; Hata, M; Shimizu, T; Yokota, H; Akatsu, H; Yamamoto, T; Kosaka, K; Yamada, T (2005). "Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix". Biochemical and Biophysical Research Communications. 335 (2): 631–6. PMID 16098915. doi:10.1016/j.bbrc.2005.07.117.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

Leucine rich repeat containing 15

References

Further reading