LYL1

LYL1
Identifiers
AliasesLYL1, bHLHa18, lymphoblastic leukemia associated hematopoiesis regulator 1, basic helix-loop-helix family member
External IDsMGI: 96891 HomoloGene: 4078 GeneCards: LYL1
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4066

17095

Ensembl

ENSG00000104903

ENSMUSG00000034041

UniProt

P12980

P27792

RefSeq (mRNA)

NM_005583

NM_008535

RefSeq (protein)

NP_005574

NP_032561

Location (UCSC)Chr 19: 13.1 – 13.1 MbChr 8: 84.7 – 84.7 Mb
PubMed search[1][2]
Wikidata
View/Edit HumanView/Edit Mouse

Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.[3][4]

Interactions

LYL1 has been shown to interact with TCF3[5] and NFKB1.[6]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Mellentin JD, Smith SD, Cleary ML (Aug 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. PMID 2752424. doi:10.1016/0092-8674(89)90404-2.
  4. "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".
  5. Miyamoto, A; Cui X; Naumovski L; Cleary M L (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Mol. Cell. Biol. UNITED STATES. 16 (5): 2394–401. ISSN 0270-7306. PMC 231228Freely accessible. PMID 8628307. doi:10.1128/mcb.16.5.2394.
  6. Ferrier, R; Nougarede R; Doucet S; Kahn-Perles B; Imbert J; Mathieu-Mahul D (Jan 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. ENGLAND. 18 (4): 995–1005. ISSN 0950-9232. PMID 10023675. doi:10.1038/sj.onc.1202374.

Further reading


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