LANCL1
LANCL1 | |||||||||||||||||
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Identifiers | |||||||||||||||||
Aliases | LANCL1, GPR69A, p40, LanC like 1 | ||||||||||||||||
External IDs | MGI: 1336997 HomoloGene: 4417 GeneCards: LANCL1 | ||||||||||||||||
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Orthologs | |||||||||||||||||
Species | Human | Mouse | |||||||||||||||
Entrez | |||||||||||||||||
Ensembl | |||||||||||||||||
UniProt | |||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||
RefSeq (protein) | |||||||||||||||||
Location (UCSC) | Chr 2: 210.43 – 210.48 Mb | Chr 1: 67 – 67.04 Mb | |||||||||||||||
PubMed search | [1] | [2] | |||||||||||||||
Wikidata | |||||||||||||||||
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LanC like 1 is a protein that in humans is encoded by the LANCL1 gene. [3]
Function
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: LanC like 1". Retrieved 2016-04-20.
Further reading
- Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC (2009). "Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione". Genes Dev. 23 (12): 1387–92. PMC 2701572 . PMID 19528316. doi:10.1101/gad.1789209.
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