Kuguaglycoside
A kuguaglycoside is one of several chemical compounds (cucurbitane triterpenoid glycosides) isolated from the roots of the bitter melon vine (Momordica charantia, kǔguā in Chinese) by J.-C. Chen and others.[1]
Kuguaglycosides are glycosides of triterpene derivatives, with the cucurbitane skeleton. They are colorless solids, soluble in methanol, ethyl acetate, and butanol.[1] They include:
- Kuguaglycoside A: 3β-hydroxy-7β-methoxycucurbita-5,24-dien-23-yl β-glucopyranoside, C
37H
62O
8[1] - Kuguaglycoside B: 3β-hydroxy-25-methoxycucurbita-5,23-dien-7β-yl β-glucopyranoside, C
37H
62O
8[1] - Kuguaglycoside C: 7β-(β-glucopyranosyloxy)-3β-hydroxycucurbita-5,23,25-trien-19-al, C3
6H
56O
8 (colorless needles)[1] - Kuguaglycoside D: 3β,19,23-trihydroxycucurbita-5,24-dien-7β-yl β-glucopyranoside, C
36H
60O
9[1] - Kuguaglycoside E: 23-(β-glucopyranosyloxy)-3β,19-dihydroxycucurbita-5,24-dien-7β-yl β-glucopyranoside, C
42H
70O
14[1] - Kuguaglycoside F: 23-(β-glucopyranosyloxy)-7β-methoxycucurbita-5,24-dien-3β-yl β-allopyranoside, C
43H
72O
13[1] - Kuguaglycoside G: 23-(β-glucopyranosyloxy)-3β-hydroxycucurbita-5,24-dien-7β-yl β-glucopyranoside, C
42H
70O
13[1] - Kuguaglycoside H: 23-(β-glucopyranosyl(1→2)-β-glucopyranosyl)-3β-hydroxycucurbita-5,24-dien-7β-yl β-glucopyranoside, C
48H
80O
18 (colorless needles)[1]
Kuguaglycoside B is also found in the fruit of M. charantia.[2]
References
- 1 2 3 4 5 6 7 8 9 10 Jian-Chao Chen, Lu Lu, Xian-Ming Zhang, Lin Zhou, Zhong-Rong Li, and Ming-Hua Qiu (2008), "Eight New Cucurbitane Glycosides, Kuguaglycosides A–H, from the Root of Momordica charantia L.". Helvetica Chimica Acta, volume 91, issue 5, pages 920-928. doi:10.1002/hlca.200890097
- ↑ Jie-Qing Liu, Jian-Chao Chen, Cui-Fang Wang and Ming-Hua Qiu (2009), "New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia". Molecules, volume 14, pages 4804-4813 doi:10.3390/molecules14124804
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