Kathie L. Olsen

Kathie L. Olsen is an American neuroscientist who is noted for her work in scientific policy. Between August 2005 and January 2009, she was the Deputy Director and Chief Operating Officer of the National Science Foundation, a United States government agency.^[1] She serves on the Advisory Board of the Journal of Science Policy & Governance.^[2]

Significant publications

Book

• Haug, M, R. Whalen, R.E; Aron, Cl., and Olsen, K (Eds.). The Development of Sex Differences and Similarities in Behaviour. Kluwar Academic Publishers, Dordrecht/Boston/London, 1993.

Book Chapters

• Olsen, K.L. and Carlson, A., "Federal Science Policy: A Perspective from Inside the Beltway" In Defining Values for Research and Technology-The University's Changing Role. Greenough, W.T, McConnaughay, P. J., and Kesan, J. P. Rowman & Littlefield Publishers, NY, Champaign-Urbana, 2007.
• Olsen, K.L., "Sex and the Mutant Mouse: Strategies for Understanding the Sexual Differentiation of the Brain," in NATO Advanced Research Workshop: The Development of Sex Differences and Similarities in Behaviour. M. Haug, R. Whalen, Cl. Aron, and K.L. Olsen (Eds.) The Development of Sex Differences and Similarities in Behaviour. Kluwar Academic Publishers, Dordrecht/Boston/London, 1993.
• Olsen, K.L., "Genetic Influences on Sexual Behavior Differentiation," in Sexual Differentiation: A Life-Span Approach, Handbook of Neurobiology. Handbook of Behavioral Neurobiology. A. Gerall, H. Moltz, and I.L. Ward (Eds.) 10, pp. 1–40, Plenum Press, 1992.
• Olsen, K.L., "Aromatization: Is It Critical for Differentiation of Sexually Dimorphic Behaviors?" in Neurobiology, R. Gilles and J. Balthazart (Eds.) Springer-Verlag, Berlin/Heidelberg, pp. 149–164, 1985.
• Olsen, K.L., "Genetic Determinants of Sexual Differentiation," in Hormones and Behavior in Higher Vertebrates, J. Balthazart, E. Prove, and R. Gilles (Eds.) Springer-Verlag, Heidelberg, pp. 138–158, 1983.
• Fox, T.O., Olsen, K.L., Vito, C.C., and Wieland, S.J., "Putative Steroid Receptors: Genetics and Development," in Molecular Genetics and Neurosciences: A New Hybrid, F.O. Schmitt, S.J. Bird, and F.E. Bloom (Eds.), Raven Press, New York, pp. 289–306, 1982.

Significant Articles

• Olsen, Kathie. L.; Neysa M. Call; Melissa A. Summers; and Ann B. Carlson. The Evolution of Excellence: Policies, Paradigms, and Practices Shaping U.S. Research and Development. In China, India, and the United States (Special Issue). Technology in Society: An International Journal. Vol. 30, No. 3-4, 2008.
• Silver, R.; Boahen, K.; Grillner, S.; Kopell, N.; Olsen, K. L. (2007). "Neurotech for Neuroscience: Unifying Concepts, Organizing Principles, and Emerging Tools". Journal of Neuroscience. 27 (44): 11807–11819. PMC 3275424 . PMID 17978017. doi:10.1523/JNEUROSCI.3575-07.2007. 
• Goldin, D. S.; Dahl, C. A.; Olsen, K. L.; Ostrach, L. H.; Klausner, R. D. (2001). "Biomedicine. The NASA-NCI collaboration on biomolecular sensors". Science. 292 (5516): 443–444. PMID 11330296. doi:10.1126/science.1059744. 
• Charest, N. J.; Zhou, Z. X.; Lubahn, D. B.; Olsen, K. L.; Wilson, E. M.; French, F. S. (1991). "A frameshift mutation destabilizes androgen receptor messenger RNA in the Tfm mouse". Molecular endocrinology (Baltimore, Md.). 5 (4): 573–581. PMID 1681426. doi:10.1210/mend-5-4-573. 
• Yarbrough, W. G.; Quarmby, V. E.; Simental, J. A.; Joseph, D. R.; Sar, M.; Lubahn, D. B.; Olsen, K. L.; French, F. S.; Wilson, E. M. (1990). "A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat". The Journal of Biological Chemistry. 265 (15): 8893–8900. PMID 2341409. 
• Olsen, K. L.; Heydorn, W. E.; Rodriguez-Sierra, J. F.; Jacobowitz, D. M. (1989). "Quantification of proteins in discrete brain regions of androgen-insensitive testicular feminized Tfm mice". Neuroendocrinology. 50 (4): 392–399. PMID 2812273. doi:10.1159/000125254. 
• Olsen, K. L.; Edwards, E.; Schechter, N.; Whalen, R. E. (1988). "Muscarinic receptors in preoptic area and hypothalamus: Effects of cyclicity, sex and estrogen treatment". Brain Research. 448 (2): 223–229. PMID 3378147. doi:10.1016/0006-8993(88)91259-0. 
• Olsen, K. L. (1988). "A comparison of the effects of three androgens on sexual differentiation in female hamsters". Physiology & Behavior. 42 (6): 569–573. PMID 3261873. doi:10.1016/0031-9384(88)90159-x. 
• Whalen, R. E.; Gladue, B. A.; Olsen, K. L. (1986). "Lordotic behavior in male rats: Genetic and hormonal regulation of sexual differentiation". Hormones and Behavior. 20 (1): 73–82. PMID 3957262. doi:10.1016/0018-506x(86)90030-9. 
• Olsen, K. L.; Whalen, R. E. (1984). "Dihydrotestosterone activates male mating behavior in castrated King-Holtzman rats". Hormones and Behavior. 18 (4): 380–392. PMID 6519654. doi:10.1016/0018-506x(84)90024-2. 
• Olsen, K. L. (1983). "Effects of 17 beta-hydroxy-17 alpha-methyl-estra-4,9,11-triene-3-one (R 1881): Evidence for direct involvement of androgens in the defeminization of behaviour in rats". The Journal of endocrinology. 98 (3): 431–438. PMID 6604780. doi:10.1677/joe.0.0980431. 
• Olsen, K. L.; Whalen, R. E. (1982). "Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats". Experientia. 38 (1): 139–140. PMID 7056359. doi:10.1007/bf01944575. 
• Olsen, K. L.; Whalen, R. E. (1981). "Hormonal control of the development of sexual behavior in androgen-insensitive (tfm) rats". Physiology & Behavior. 27 (5): 883–886. PMID 7323196. doi:10.1016/0031-9384(81)90058-5. 
• Whalen, R. E.; Olsen, K. L. (1981). "Role of aromatization in sexual differentiation: Effects of prenatal ATD treatment and neonatal castration". Hormones and Behavior. 15 (2): 107–122. PMID 7250905. doi:10.1016/0018-506x(81)90022-2. 
• Olsen, K. L.; Whalen, R. E. (1980). "Sexual differentiation of the brain: Effects on mating behavior and 3H-estradiol binding by hypothalamic chromatin in rats". Biology of Reproduction. 22 (5): 1068–1072. PMID 7417642. doi:10.1095/biolreprod22.5.1068. 
• Olsen, K. L. (1979). "Induction of male mating behavior in androgen-insensitive (tfm) and Normal (King-Holtzman) male rats: Effect of testosterone propionate, estradiol benzoate, and dihydrotestosterone". Hormones and Behavior. 13 (1): 66–84. PMID 521021. doi:10.1016/0018-506x(79)90035-7. 
• Olsen, K. L. (1979). "Androgen-insensitive rats are defeminised by their testes". Nature. 279 (5710): 238–239. PMID 440434. doi:10.1038/279238a0. 
• Whalen, R. E.; Olsen, K. L. (1978). "Prednisolone modifies estrogen-induced sexual differentiation". Behavioral Biology. 24 (4): 549–553. PMID 747592. doi:10.1016/s0091-6773(78)91023-4. 
• Whalen, R. E.; Olsen, K. L. (1978). "Chromatin binding of estradiol in the hypothalamus and cortex of male and female rats". Brain Research. 152 (1): 121–131. PMID 679020. doi:10.1016/0006-8993(78)90138-5. 
• Whalen, R. E.; Martin, J. V.; Olsen, K. L. (1975). "Effect of oestrogen antagonist on hypothalamic oestrogen receptors". Nature. 258 (5537): 742–743. PMID 174000. doi:10.1038/258742a0. 

PhD Thesis

• Hormonal mechanisms controlling the development and regulation of male-female differences, Doctoral thesis, 1979

See also

• National Science Foundation
• National Aeronautics and Space Administration (NASA)

References

External links

• Kathie L. Olsen's National Science Foundation Biography
• ScienceWorks DC