Karen Duff

Karen Duff
Born 1965 (age 5152)
Fields Pathology
Cell Biology
Institutions Columbia University
New York University
University of South Florida
Alma mater University of East Anglia
Queens' College, Cambridge
Thesis A study of human and murine cardiac development using molecular genetics methodology (1991)
Notable awards Potamkin Prize (2006)
Website
Karen Duff, Ph.D.

Karen Elizabeth Keitley Duff (born 1965) is a British scientist known for her work on Alzheimer's disease. She is currently Professor of Pathology and Cell Biology at Columbia University.[1] Her most notable work focused on the development and characterization of mouse models of Alzheimer's disease amyloid deposition.[2][3]

She was educated at the University of East Anglia (BSc, 1987) and completed her PhD at Queens' College, Cambridge in 1991 entitled "A study of human and murine cardiac development using molecular genetics methodology". At Cambridge she was a student of Sydney Brenner's department. She was awarded the Potamkin Prize in 2006, together with Karen Ashe and Bradley Hyman.[4]

References

  1. "Karen Duff, Ph.D. - Professor of Pathology & Cell Biology". Columbia University. Retrieved 6 August 2014.
  2. Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K (Jan 1998). "Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes". Nat Med. 4 (1): 97–100. PMID 9427614.
  3. Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S (Oct 1996). "Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1". Nature. 383 (6602): 710–3. PMID 8878479. doi:10.1038/383710a0.
  4. "Karen Duff Receives Prestigious Prize for Alzheimer's Research". NYU Langone Medical Center. Retrieved 6 August 2014.
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