KRR1

KRR1

Identifiers

KRR1, HRB2, RIP-1, small subunit processome component homolog

External IDs

MGI: 1289274 HomoloGene: 5114 GeneCards: KRR1

Gene ontology
Molecular function	• protein binding • nucleic acid binding • RNA binding
Cellular component	• cytoplasm • small-subunit processome • intracellular ribonucleoprotein complex • nucleolus • membrane • nucleus • intercellular bridge • nucleoplasm
Biological process	• ribosome biogenesis • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • rRNA processing
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


11103


52705


ENSG00000111615


ENSMUSG00000063334


Q13601


Q8BGA5

RefSeq (mRNA)


NM_007043


NM_178610

RefSeq (protein)


NP_008974


NP_848725

Location (UCSC)

Chr 12: 75.49 – 75.51 Mb

Chr 10: 111.97 – 111.99 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

KRR1 small subunit processome component homolog is a protein that in humans is encoded by the KRR1 gene.^[3]^[4]^[5]^[6]^[7]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Epplen C, Epplen JT (Feb 1994). "Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes". Hum Genet. 93 (1): 35–41. PMID 7505766. doi:10.1007/BF00218910.
↑ Sasaki T, Toh-E A, Kikuchi Y (Oct 2000). "Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus". Mol Cell Biol. 20 (21): 7971–9. PMC 86407 . PMID 11027267. doi:10.1128/MCB.20.21.7971-7979.2000.
↑ Chan HY, Brogna S, O'Kane CJ (May 2001). "Dribble, the Drosophila KRR1p Homologue, Is Involved in rRNA Processing". Mol Biol Cell. 12 (5): 1409–19. PMC 34593 . PMID 11359931. doi:10.1091/mbc.12.5.1409.
↑ Gromadka R, Kaniak A, Slonimski PP, Rytka J (Aug 1996). "A novel cross-phylum family of proteins comprises a KRR1 (YCL059c) gene which is essential for viability of Saccharomyces cerevisiae cells". Gene. 171 (1): 27–32. PMID 8675026. doi:10.1016/0378-1119(96)00024-8.
↑ "Entrez Gene: KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)".

Further reading

Muthumani K, Choo AY, Premkumar A, et al. (2006). "Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism". Cell Death Differ. 12 Suppl 1: 962–70. PMID 15832179. doi:10.1038/sj.cdd.4401583.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. PMID 11790298. doi:10.1016/S0960-9822(01)00650-9.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. PMC 133617 . PMID 12429849. doi:10.1091/mbc.E02-05-0271.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Micheau O, Tschopp J (2003). "Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes". Cell. 114 (2): 181–90. PMID 12887920. doi:10.1016/S0092-8674(03)00521-X.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Bernstein KA, Gallagher JE, Mitchell BM, et al. (2005). "The Small-Subunit Processome Is a Ribosome Assembly Intermediate". Eukaryotic Cell. 3 (6): 1619–26. PMC 539036 . PMID 15590835. doi:10.1128/EC.3.6.1619-1626.2004.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. PMID 15635413. doi:10.1038/nature03207.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. PMID 16341674. doi:10.1007/s00335-005-0075-2.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.

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