KLF8
Krueppel-like factor 8 is a protein that in humans is encoded by the KLF8 gene.[3]
Interactions
KLF8 has been shown to interact with CTBP2.[4]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: KLF8 Kruppel-like factor 8".
- ↑ van Vliet J, Turner J, Crossley M (May 2000). "Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription". Nucleic Acids Research. 28 (9): 1955–62. PMC 103308
. PMID 10756197. doi:10.1093/nar/28.9.1955.
Further reading
- van Vliet J, Turner J, Crossley M (May 2000). "Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription". Nucleic Acids Research. 28 (9): 1955–62. PMC 103308 . PMID 10756197. doi:10.1093/nar/28.9.1955.
- Lossi AM, Laugier-Anfossi F, Depetris D, Gecz J, Gedeon A, Kooy F, Schwartz C, Mattei MG, Croquette MF, Villard L (Feb 2002). "Abnormal expression of the KLF8 (ZNF741) gene in a female patient with an X;autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation". Journal of Medical Genetics. 39 (2): 113–7. PMC 1735036 . PMID 11836360. doi:10.1136/jmg.39.2.113.
- Turner J, Nicholas H, Bishop D, Matthews JM, Crossley M (Apr 2003). "The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2". The Journal of Biological Chemistry. 278 (15): 12786–95. PMID 12556451. doi:10.1074/jbc.M300587200.
- Zhao J, Bian ZC, Yee K, Chen BP, Chien S, Guan JL (Jun 2003). "Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression". Molecular Cell. 11 (6): 1503–15. PMID 12820964. doi:10.1016/S1097-2765(03)00179-5.
- Zhang P, Basu P, Redmond LC, Morris PE, Rupon JW, Ginder GD, Lloyd JA (2006). "A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element". Blood Cells, Molecules & Diseases. 35 (2): 227–35. PMID 16023392. doi:10.1016/j.bcmd.2005.04.009.
- Wang X, Zhao J (Jan 2007). "KLF8 transcription factor participates in oncogenic transformation". Oncogene. 26 (3): 456–61. PMID 16832343. doi:10.1038/sj.onc.1209796.
- Hu JH, Navas P, Cao H, Stamatoyannopoulos G, Song CZ (Mar 2007). "Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation". Journal of Molecular Biology. 366 (4): 1064–73. PMC 1907364 . PMID 17224162. doi:10.1016/j.jmb.2006.12.047.
- Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J (Aug 2007). "Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion". Cancer Research. 67 (15): 7184–93. PMID 17671186. doi:10.1158/0008-5472.CAN-06-4729.
External links
- KLF8 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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