Itabaianinha

Coordinates: 11°16′26″S 37°47′24″W / 11.27389°S 37.79000°W / -11.27389; -37.79000

Itabaianinha is a municipality located in the Brazilian state of Sergipe. Its population was 38,886 (2012) and its area is 493 km².[1]

Itabaianinha is noted for its large dwarf population. It is sometimes called "a cidade dos anões" ("the city of dwarfs").[2] The dwarfism is of the proportionate type and arises from a rare genetic mutation.[3] The population probably originated through intrafamily marriages. The condition has been shown[4] to have no effect on normal lifespan. In the late 1990s many residents of Itabaianinha under 15 years started receiving hormonal treatment. The population of dwarfs is dwindling, with only an estimated one hundred remaining, mostly in the village of Carretéis, ten miles from Itabaianinha center.[5]

References

  1. ↑ IBGE - "Archived copy". Archived from the original on 2007-01-09. Retrieved 2014-08-03.
  2. ↑ Gonzalez-Ramirez, Andrea (1 September 2016). "Inside The City With The World's Largest Population Of People With Dwarfism — In Photos". Refinery29.
  3. ↑ Hayashida, CY; Gondo, RG; Ferrari, C; Toledo, SP; Salvatori, R; Levine, MA; Ezabella, MC; Abelin, N; Gianella-Neto, D; Wajchenberg, BL (June 2000). "Familial growth hormone deficiency with mutated GHRH receptor gene: clinical and hormonal findings in homozygous and heterozygous individuals from Itabaianinha.". European journal of endocrinology / European Federation of Endocrine Societies. 142 (6): 557–63. PMID 10822217.
  4. ↑ "Human Growth Hormone: Not a Life Extender After All?". Johns Hopkins Medicine. 26 January 2010.
  5. ↑ Paolini, Giulia Valentina; Pitzalis, Bruno (19 November 2014). "City of Dwarfs". Narratively.
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