Isoniazid/rifampicin
| Combination of | |
|---|---|
| Isoniazid | Anti-tuberculosis medication |
| Rifampicin | Anti-tuberculosis medication |
| Clinical data | |
| Trade names | IsonaRif, Rifamate, others |
| Pregnancy category |
|
| ATC code | |
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. It is a fixed dose combination of isoniazid and rifampicin (rifampin). It is used together with other antituberculosis medication. It is taken by mouth.[1]
Side effects are those of the underlying medications.[1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired.[2] More severe side effects include liver problems.[2] Use is generally not recommended in children.[1] It is unclear if use is safe in pregnancy.[3]
It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[4] The wholesale cost in the developing world is about 5.10 USD a month.[5] In the United Kingdom a month of medication costs the NHS about 28.11 pounds.[6]
References
- 1 2 3 WHO Model Formulary 2008 (PDF). World Health Organization. 2009. p. 142. ISBN 9789241547659. Retrieved 8 December 2016.
- 1 2 "Isoniazid/rifampin Side Effects in Detail - Drugs.com". www.drugs.com. Retrieved 18 December 2016.
- ↑ "Isoniazid / rifampin Use During Pregnancy | Drugs.com". www.drugs.com. Retrieved 18 December 2016.
- ↑ "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Retrieved 8 December 2016.
- ↑ "Rifampicin + Isoniazid". International Drug Price Indicator Guide. Retrieved 8 December 2016.
- ↑ British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 403. ISBN 9780857111562.