Iotroxic acid
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| Clinical data | |
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| Trade names | Biliscopin, others |
| AHFS/Drugs.com | International Drug Names |
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| ChEMBL | |
| ECHA InfoCard | 100.051.726 |
| Chemical and physical data | |
| Formula | C22H18I6N2O9 |
| Molar mass | 1215.81314 g/mol |
| 3D model (JSmol) | |
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Iotroxic acid, also known as meglumine iotroxate, is a molecule used as a contrast medium during X-rays.[1][2] It is specifically used during tests looking at the gallbladder and biliary tract. It is given by slow injection into a vein.[2]
Side effects are uncommon.[3] They include vomiting, skin flushing, headache, itchiness, and low blood pressure. Rare side effects include seizures and allergic reactions. It should not be used by those who have a iodine allergy.[2] Iotroxic acid is an iodine containing contrast media of the diionic dimer type.[4]
Iotroxic acid was first made in 1976.[5] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[6] It is rarely used in the developed world due to the availability of magnetic resonance cholangiopancreatography (MRCP).[7]
References
- ↑ "Iotroxic Acid - Drugs.com". www.drugs.com. Retrieved 31 December 2016.
- 1 2 3 WHO Model Formulary 2008 (PDF). World Health Organization. 2009. pp. 315, 318. ISBN 9789241547659. Retrieved 8 December 2016.
- ↑ Neugebauer, Edmund; Sauerland, Stefan (2014). Recommendations for evidence-based endoscopic surgery: The updated EAES consensus development conferences. Springer Science & Business Media. p. 67. ISBN 9782817808499.
- ↑ Schaefer, Christof; Peters, Paul W. J.; Miller, Richard K. (2014). Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. Academic Press. p. 532. ISBN 9780124079014.
- ↑ Korolkovas, Andrejus (1988). Essentials of Medicinal Chemistry. Wiley. p. 1063. ISBN 9780471883562.
- ↑ "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Retrieved 8 December 2016.
- ↑ Sherlock, Shiela; Dooley, James (2008). Diseases of the Liver and Biliary System. John Wiley & Sons. p. 568. ISBN 9780470986813.