Interferon-inducible GTPase 5

IRGC

Identifiers

IRGC, CINEMA, IFGGE, IRGC1, Iigp5, R30953_1, immunity related GTPase cinema

External IDs

MGI: 2685948 HomoloGene: 10486 GeneCards: IRGC

Gene location (Human)

Chr.	Chromosome 19 (human)^[1]

Band	No data available	Start	43,716,010 bp^[1]
Band	No data available	End	43,720,021 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 7 (mouse)^[2]

Band	No data available	Start	24,431,922 bp^[2]
Band	No data available	End	24,452,297 bp^[2]

Orthologs

Species

Human

Mouse

Entrez


56269


210145

Ensembl


ENSG00000124449


ENSMUSG00000062028

UniProt


Q6NXR0


Q8C262

RefSeq (mRNA)


NM_019612


NM_199013

RefSeq (protein)


NP_062558


n/a

Location (UCSC)

Chr 19: 43.72 – 43.72 Mb

Chr 7: 24.43 – 24.45 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Interferon-inducible GTPase 5 also known as immunity-related GTPase cinema 1 (IRGC1) is an enzyme that in humans is encoded by the IRGC gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000124449 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062028 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Immunity-related GTPase family, cinema". Retrieved 2011-12-16.

Cu++ (3.6.3.4)	Menkes/ATP7A Wilson/ATP7B
Ca+ (3.6.3.8)	SERCA ATP2A1 ATP2A2 ATP2A3 Plasma membrane ATP2B1 ATP2B2 ATP2B3 ATP2B4 SPCA ATP2C1 ATP2C2
Na+/K+ (3.6.3.9)	ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4
H+/K+ (3.6.3.10)	ATP4A
Other P-type ATPase	ATP8B1 ATP10A ATP11B ATP12A ATP13A2 ATP13A3

3.6.4

3.6.5: GTPase

3.6.5.1: Heterotrimeric G protein	G_αs G_αi GNAI1 GNAI2 GNAI3 G_αq/11 GNAQ GNA11 G_α12/13 GNA12 GNA13 Transducin GNAT1 GNAT2 Gustducin GNAT3
3.6.5.2: Small GTPase > Ras superfamily	Rho family of GTPases: Cdc42 CDC42 TC10 TCL RhoUV RhoU RhoV Rac Rac1 2 3 RhoG RhoBTB 1 2 RhoH Rho A B C Rnd 1 2 3 RhoDF RhoF RhoD other: Ras HRAS KRAS NRAS Rab RAB23 RAB27 Arf ARF6 SAR1B ARL13B ARL6 Ran Rheb Rap RGK
3.6.5.3: Protein-synthesizing GTPase	Prokaryotic IF-2 EF-Tu EF-G Eukaryotic
3.6.5.5-6: Polymerization motors	Dynamin Tubulin

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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Interferon-inducible GTPase 5

References

Further reading