Integrin alphaXbeta2

Integrin alphaXbeta2 (p150,95, CR4) is a complement receptor composed of CD11c and CD18.

External links

Integrin alphaXbeta2 at the US National Library of Medicine Medical Subject Headings (MeSH)

Proteins: complement system (C, L, A)

Activators/enzymes

Early	C: C1Q/C1R/C1S C4 C4a C4b C2 L: MASP1/MASP2 MBL A: Factor B Factor D Factor P/Properdin
Middle	C3 C3a C3b/iC3b C5 C5a C3-convertase C5-convertase
Late	MAC C6 C7 C8 C9

Inhibitors

CL: C4BP

A: Factor H

Complement receptors

Membrane proteins: cell adhesion molecules

Calcium-independent

IgSF CAM	N-CAM (Myelin protein zero) ICAM (1, 5) VCAM-1 PE-CAM L1-CAM Nectin (PVRL1, PVRL2, PVRL3)
Integrins	LFA-1 (CD11a+CD18) Integrin alphaXbeta2 (CD11c+CD18) Macrophage-1 antigen (CD11b+CD18) VLA-4 (CD49d+CD29) Glycoprotein IIb/IIIa (ITGA2B+ITGB3)

Calcium-dependent

Classical	CDH1 CDH2 CDH3
Desmosomal	Desmoglein (DSG1, DSG2, DSG3, DSG4) Desmocollin (DSC1, DSC2, DSC3)
Protocadherin	PCDH1 PCDH15
Unconventional/ungrouped	T-cadherin CDH4 CDH5 CDH6 CDH8 CDH11 CDH12 CDH15 CDH16 CDH17 CDH9 CDH10

Other

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