Inositol phosphate

Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:

inositol monophosphate (IP)
inositol bisphosphate (IP₂)
inositol trisphosphate (IP₃)
inositol pentakisphosphate (IP₅)
inositol hexaphosphate (IP₆) also known as phytic acid, or phytate (as a salt).

Functions

Inositol triphosphate

Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans

Other

Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression^[1] and Steger^[2] (both in Science Magazine).

References

↑ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science. 299 (5603): 112–4. PMID 12434013. doi:10.1126/science.1078068.
↑ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science. 299 (5603): 114–6. PMC 1458531 . PMID 12434012. doi:10.1126/science.1078062.

External links

Lipids: phospholipids

Glycerol backbone
(Glycerophospholipids/
Phosphoglycerides)

Phosphatidyl-:	-ethanolamine/cephalin (PE) -choline/lecithin (PC) -serine (PS) -glycerol (PG) -inositol (PI) glyco- (GPI)
Phosphoinositides:	PIP PI(3)P PI(4)P PI(5)P PIP₂ PI(3,4)P₂ PI(3,5)P₂ PI(4,5)P₂ PIP₃
Ether lipids:	Plasmalogen Platelet-activating factor
Cardiolipin

Sphingosine backbone

Sphingomyelin

Metabolites

Inositol phosphate Inositol
Lysophosphatidic acid
Choline Phosphocholine Citicoline

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.