Impromidine
Impromidine
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Clinical data |
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ATC code |
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Identifiers |
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- 2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
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CAS Number |
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IUPHAR/BPS |
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ChEMBL |
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Chemical and physical data |
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Formula |
C14H23N7S |
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Molar mass |
321.44 g/mol |
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3D model (JSmol) |
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Cc2ncnc2CSCCNC(N)=NCCCc1cncn1
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InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) NKey:MURRAGMMNAYLNA-UHFFFAOYSA-N N
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NY (what is this?) (verify) |
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Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.[1]
It has been used diagnostically as a gastric secretion indicator.
See also
References
- ↑ Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. PMID 714166. doi:10.1038/276403a0.
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H1 |
- Non-generational: Atypical antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, clozapine, iloperidone, olanzapine, paliperidone, quetiapine, risperidone, RP-5063, ziprasidone, zotepine)
- Tetracyclic antidepressants (e.g., amoxapine, loxapine, maprotiline, mianserin, mirtazapine, oxaprotiline)
- Tricyclic antidepressants (e.g., amitriptyline, butriptyline, clomipramine, desipramine, dosulepin (dothiepin), doxepin, imipramine, iprindole, lofepramine, nortriptyline, protriptyline, trimipramine)
- Typical antipsychotics (e.g., chlorpromazine, flupenthixol, fluphenazine, loxapine, perphenazine, prochlorperazine, thioridazine, thiothixene)
- Unknown/unsorted: Belarizine
- Elbanizine
- Flotrenizine
- Napactadine
- Tagorizine
- Trelnarizine
- Trenizine
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H2 | |
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H3 | |
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H4 | |
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See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake and release modulators |