Iboga alkaloid

Iboga alkaloids are alkaloid constituents of Tabernanthe iboga. Iboga alkaloids include ibogaine, tabernanthine, coronaridine, voacangine, ibogamine, and harmaline, among others. Noribogaine is a major active metabolite of ibogaine, and 18-methoxycoronaridine is a synthetic derivative of coronaridine.[1][2]

References

  1. ↑ Seifert, Roland; Antonio, Tamara; Childers, Steven R.; Rothman, Richard B.; Dersch, Christina M.; King, Christine; Kuehne, Martin; Bornmann, William G.; Eshleman, Amy J.; Janowsky, Aaron; Simon, Eric R.; Reith, Maarten E. A.; Alper, Kenneth (2013). "Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation". PLoS ONE. 8 (10): e77262. ISSN 1932-6203. PMC 3818563 Freely accessible. PMID 24204784. doi:10.1371/journal.pone.0077262.
  2. ↑ Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW, Carlson JN (1994). "Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum". Brain Res. 657 (1-2): 14–22. PMID 7820611. doi:10.1016/0006-8993(94)90948-2.


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