ITM2C

Identifiers

ITM2C, BRI3, BRICD2C, E25, E25C, ITM3, integral membrane protein 2C

External IDs

MGI: 1927594 HomoloGene: 11186 GeneCards: ITM2C

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	No data available	Start	230,864,639 bp^[1]
Band	No data available	End	230,879,248 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	No data available	Start	85,894,281 bp^[2]
Band	No data available	End	85,908,675 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• amyloid-beta binding • protein binding • ATP binding
Cellular component	• perinuclear region of cytoplasm • integral component of membrane • lysosomal membrane • extracellular exosome • membrane • lysosome • plasma membrane • Golgi apparatus
Biological process	• positive regulation of extrinsic apoptotic signaling pathway • negative regulation of neuron projection development • neuron differentiation • negative regulation of amyloid precursor protein biosynthetic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


81618


64294

Ensembl


ENSG00000135916


ENSMUSG00000026223

UniProt


Q9NQX7


Q91VK4

RefSeq (mRNA)


NM_030926 NM_001012514 NM_001012516 NM_001287240 NM_001287241


NM_022417

RefSeq (protein)


NP_001012532 NP_001012534 NP_001274169 NP_001274170 NP_112188


NP_071862

Location (UCSC)

Chr 2: 230.86 – 230.88 Mb

Chr 1: 85.89 – 85.91 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Integral membrane protein 2C is a protein that in humans is encoded by the ITM2C gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000135916 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026223 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z (Aug 1998). "Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc Natl Acad Sci U S A. 95 (14): 8175–80. PMC 20949 . PMID 9653160. doi:10.1073/pnas.95.14.8175.
↑ "Entrez Gene: ITM2C integral membrane protein 2C".

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ITM2C

References

Further reading