ITGB3BP

ITGB3BP
Identifiers
AliasesITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20, integrin subunit beta 3 binding protein
External IDsMGI: 1914983 HomoloGene: 8617 GeneCards: ITGB3BP
Gene location (Human)
Chr.Chromosome 1 (human)[1]
BandNo data availableStart63,440,770 bp[1]
End63,593,721 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23421

67733

Ensembl

ENSG00000142856

ENSMUSG00000028549

UniProt

Q13352

Q9CQ82

RefSeq (mRNA)

NM_001206739
NM_014288
NM_001347145
NM_001347147
NM_001347148

NM_026348

RefSeq (protein)

NP_001193668
NP_001334074
NP_001334076
NP_001334077
NP_055103

NP_080624

Location (UCSC)Chr 1: 63.44 – 63.59 MbChr 4: 99.77 – 99.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.[5][6][7]

Interactions

ITGB3BP has been shown to interact with:

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000142856 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028549 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. 1 2 Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell Biol. 131 (3): 807–16. PMC 2120613Freely accessible. PMID 7593198. doi:10.1083/jcb.131.3.807.
  6. 1 2 3 Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (February 2000). "NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors". Mol Cell Biol. 19 (10): 7191–202. PMC 84712Freely accessible. PMID 10490654. doi:10.1128/mcb.19.10.7191.
  7. "Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)".
  8. Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. 105 (1): 63–70. PMID 11864709. doi:10.1016/s0049-3848(01)00405-4.
  9. Ohtoshi A, Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (January 2000). "beta3-endonexin as a novel inhibitor of cyclin A-associated kinase". Biochem. Biophys. Res. Commun. 267 (3): 947–52. PMID 10673397. doi:10.1006/bbrc.1999.2007.
  10. Besta F, Massberg S, Brand K, Müller E, Page S, Grüner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E, Gawaz M (October 2002). "Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell. Sci. 115 (Pt 20): 3879–88. PMID 12244126. doi:10.1242/jcs.00081.
  11. 1 2 Li D, Wang F, Samuels HH (December 2001). "Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation". Mol. Cell. Biol. 21 (24): 8371–84. PMC 100002Freely accessible. PMID 11713274. doi:10.1128/MCB.21.24.8371-8384.2001.

Further reading


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