IFIT3

IFIT3

Identifiers

IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41, interferon induced protein with tetratricopeptide repeats 3

External IDs

MGI: 3698419 HomoloGene: 1189 GeneCards: IFIT3

Gene location (Human)

Chr.	Chromosome 10 (human)^[1]

Band	No data available	Start	89,327,894 bp^[1]
Band	No data available	End	89,340,971 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 19 (mouse)^[2]

Band	No data available	Start	34,607,970 bp^[2]
Band	No data available	End	34,613,401 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• identical protein binding • protein binding
Cellular component	• cytoplasm • mitochondrion • cytosol
Biological process	• immune system process • response to virus • innate immune response • negative regulation of apoptotic process • defense response to virus • type I interferon signaling pathway • negative regulation of cell proliferation • cellular response to interferon-alpha
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


3437


667370


ENSG00000119917


ENSMUSG00000062488


O14879


n/a

RefSeq (mRNA)


NM_001549 NM_001031683 NM_001289758 NM_001289759


NM_001005858

RefSeq (protein)


NP_001026853 NP_001276687 NP_001276688 NP_001540


n/a

Location (UCSC)

Chr 10: 89.33 – 89.34 Mb

Chr 19: 34.61 – 34.61 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Interferon-induced protein with tetratricopeptide repeats 3 is a protein that in humans is encoded by the IFIT3 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000119917 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062488 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ de Veer MJ, Sim H, Whisstock JC, Devenish RJ, Ralph SJ (Jan 1999). "IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes". Genomics. 54 (2): 267–77. PMID 9828129. doi:10.1006/geno.1998.5555.
↑ Zhu H, Cong JP, Shenk T (Jan 1998). "Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs". Proc Natl Acad Sci U S A. 94 (25): 13985–90. PMC 28419 . PMID 9391139. doi:10.1073/pnas.94.25.13985.
↑ "Entrez Gene: IFIT3 interferon-induced protein with tetratricopeptide repeats 3".

Further reading

Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. PMID 16964243. doi:10.1038/nbt1240.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Reuter TY, Medhurst AL, Waisfisz Q, et al. (2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.". Exp. Cell Res. 289 (2): 211–21. PMID 14499622. doi:10.1016/S0014-4827(03)00261-1.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191–7. PMID 12539042. doi:10.1038/nm822.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Yu M, Tong JH, Mao M, et al. (1997). "Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes.". Proc. Natl. Acad. Sci. U.S.A. 94 (14): 7406–11. PMC 23834 . PMID 9207104. doi:10.1073/pnas.94.14.7406.

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