Herbert W. "Skip" Virgin

Herbert W. "Skip" Virgin
Born	Miami, Florida
Residence	Clayton, Missouri
Fields	Virology Immunology Genetics
Institutions	Washington University School of Medicine
Alma mater	Harvard University Harvard Medical School
Doctoral advisor	Emil Unanue
Known for	Human virome Viral pathogenesis Autophagy

Herbert W. "Skip" Virgin is the Edward Mallinckrodt Professor and Chair of the Department of Pathology & Immunology at the Washington University School of Medicine^[1] and a member of the National Academy of Sciences.^[2] He is best known for establishing murine norovirus as a model system for studying norovirus biology, for identifying host phenotypes associated with persistent viral infections, for defining alterations to the human virome in the context of different diseases, and for elucidating the roles of autophagy and interferon-stimulated genes during viral infection.

Life

Dr. Virgin was born in Miami, Florida and studied biology at Harvard University as an undergraduate, graduating magna cum laude. He obtained his M.D. and Ph.D. from Harvard Medical School, with his thesis work focusing on host immune responses to Listeria monocytogenes, and completed his residency in internal medicine at Brigham and Women's Hospital.^[3] Following post-doctoral training in the laboratory of Bernard Fields, he joined the faculty of the Washington University School of Medicine. He has remained at Washington University since 1991 and is presently Chair of the Department of Pathology & Immunology.

Barton, E; White, D; Cathelyn, J; Brett-McClellan, K; Engle, M; Diamond, M; Miller, V; Virgin, H (2007). "Herpesvirus latency confers symbiotic protection from bacterial infection". Nature. 447: 326–329. PMID 17507983. doi:10.1038/nature05762.
Nice, T; Baldridge, M; McCune, B; Norman, J; Lazear, H; Artyomov, M; Diamond, M; Virgin, H (2015). "Interferon λ cures persistent murine norovirus infection in the absence of adaptive immunity". Science. 347: 269–273. PMID 25431489. doi:10.1126/science.1258100.
Orchard, R; Wilen, C; Doench, J; Baldridge, M; McCune, B; Lee, Y; Lee, S; Pruett-Miller, S; Nelson, C; Fremont, D; Virgin, H (2016). "Discovery of a proteinaceous cellular receptor for a norovirus". Science. 26: 933–936. PMID 27540007. doi:10.1126/science.aaf1220.
Norman, J; Handley, S; Baldridge, M; Droit, L; Liu, C; Keller, B; Kambal, A; Monaco, C; Zhao, G; Fleshner, P; Stappenbeck, T; McGovern, D; Keshavarzian, A; Mutlu, E; Sauk, J; Gevers, D; Xavier, R; Wang, D; Parkes, M; Virgin, H (2015). "Disease-specific alterations in the enteric viriome in inflammatory bowel disease". Cell. 160: 447–460. PMID 25619688. doi:10.1016/j.cell.2015.01.002.

↑ "Herbert Virgin IV, MD, PhD". Washington University School of Medicine. Retrieved 2016-12-31.
↑ "Herbert W. Virgin, IV". National Academy of Sciences. Retrieved 2016-12-31.
↑ "Herbert Virgin, M.D., Ph.D.". mBio Board of Editors. Retrieved 2016-12-31.

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