Hemoglobin J

Hemoglobin J is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. It was first reported in American Negro family[1] in 1956. Later on reported from Indonsia, India, and other parts of the world. Hemoglobin J reported from Meerut India shows the mutation of 120th Alanine to Glutamic acid on alpha chain.[2] Hemoglobin J was also reported from Chhattisgarh, Central India as revealed by Lingojwar and coworkers in 2016.

References

  1. ↑ Thorup, O (1956). "Hemoglobin j" (PDF). Science. 123: 889–890. doi:10.1126/science.123.3203.889. Retrieved 13 April 2016.
  2. ↑ Blackwell, R (May 10, 1974). "Hemoglobin J Meerut: alpha120 Ala leads to Glu". Biochim Biophys Acta. 351: 7–12. PMID 4600474.
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