Harmol

Harmol
Names
IUPAC name
1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.951
Properties
C12H10N2O
Molar mass 198.22 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Harmol is a β-carboline isolated from nature.[1][2][3]

References

  1. ↑ Abe A, Kokuba H (2013). "Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin.". Oncol Rep. 29 (4): 1333–42. PMID 23338618. doi:10.3892/or.2013.2242.
  2. ↑ El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO (2012). "Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol.". Toxicol Lett. 208 (1): 51–61. PMC 3263333 Freely accessible. PMID 22001777. doi:10.1016/j.toxlet.2011.09.030.
  3. ↑ Abe A, Yamada H, Moriya S, Miyazawa K (2011). "The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells.". Biol Pharm Bull. 34 (8): 1264–72. PMID 21804216. doi:10.1248/bpb.34.1264.


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