Haplogroup IWX (mtDNA)
In human genetics, Haplogroup IWX was a human mitochondrial DNA (mtDNA) haplogroup.[1][2]
It was thought to cluster haplogroups I, W, and X.[3][4] Studies suggested haplogroup IWX to be highly protective against AIDS progression.[5] It is now known that Haplogroup I is descendent of Haplogroup N1. It has also been proposed that Haplogroup W be placed as a descendant of Haplogroup N2b.[6]
References
- ↑ Maruszak A, Canter JA, Styczyńska M, Zekanowski C, Barcikowska M (November 2009). "Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?". Neurobiology of Aging. 30 (11): 1749–55. PMID 18308428. doi:10.1016/j.neurobiolaging.2008.01.004.
- ↑ The genome of Homo sapiens
- ↑ Bermisheva M, Tambets K, Villems R, Khusnutdinova E (2002). "[Diversity of mitochondrial DNA haplotypes in ethnic populations of the Volga-Ural region of Russia]" (PDF). Molekuliarnaia Biologiia (in Russian). 36 (6): 990–1001. PMID 12500536.
- ↑ Simoni L, Calafell F, Pettener D, Bertranpetit J, Barbujani G (January 2000). "Geographic patterns of mtDNA diversity in Europe" (PDF). American Journal of Human Genetics. 66 (1): 262–78. PMC 1288355 . PMID 10631156. doi:10.1086/302706.
- ↑ Hendrickson SL, Hutcheson HB, Ruiz-Pesini E, et al. (November 2008). "Mitochondrial DNA haplogroups influence AIDS progression". AIDS (London, England). 22 (18): 2429–39. PMC 2699618 . PMID 19005266. doi:10.1097/QAD.0b013e32831940bb.
- ↑ van Oven M, Kayser M (February 2009). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–94. PMID 18853457. doi:10.1002/humu.20921.
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||||
L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
M | N | ||||||||||||||||||||||||||||||||||||||
CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
HV | JT | K | |||||||||||||||||||||||||||||||||||||
H | V | J | T |
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