Ham test

The Ham test is a test used in the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH). The test involves placing red blood cells in mild acid; a positive result (increased RBC fragility) indicates PNH or Congenital dyserythropoietic anemia.[1][2] This is now an obsolete test for diagnosing PNH due to its low sensitivity and specificity.[3]

Ham's test is occasionally positive in aplastic anemia.

References

  1. ↑ Ham, Thomas H. (1937). "Chronic Hemolytic Anemia with Paroxysmal Nocturnal Hemoglobinuria". New England Journal of Medicine. 217 (23): 915–7. doi:10.1056/NEJM193712022172307.
  2. ↑ MedlinePlus Encyclopedia Ham test
  3. ↑ "Paroxysmal Nocturnal Hemoglobinuria - PNH". ARUP.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.