HLA-B59

major histocompatibility complex (human), class I, B59
Alleles B*5901
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5901
Locus chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.[1] B59 is a hybrid between B*55 and B*51.[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products[3]
B*59 B59 Other Sample
allele % % size (N)
5901 45 41 123

B*5901 allele frequencies

HLA B*5901 frequencies
freq
ref. Population (%)
[4] Okinawan (USA Hawaii)6.3
[4] Japan (2)2.7
[4] Tarialan Khoton (Mongolia)2.4
[4] South Korea (3)2.1
[4] Gipuscoa Basque (Spain)2.0
[4] Japan Central1.8
[4] Casablanca (Morocco)1.8
[4] Hyogo (Japan)1.6
[4] N. Korean (Harbin,China) 1.0
[4] Manchu (Harbin, China)0.6
[4] Naxi (Yunnan, China)0.6
[4] Girona (Catalonia,Spain) 0.6
[4] Algeria (1)0.5
[4] Inner Mongolia (China)0.5
[4] Khalkha (Mongolia)0.5
[4] Shanghai (China)0.3
[4] Essen (German )0.3
[4] Southern Han (China)0.2
[4] Shij. Tian. (Beijing, China) 0.1
[4] Hakka (Taiwan) 0.1
Regions of higher B*5901 frequency
Japan
Korea
Mongolia
Heilongjiang
prov., China
(Harbin city)

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. PMID 15787720. doi:10.1111/j.1399-0039.2005.00379.x.
  2. ↑ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. PMID 8362411. doi:10.1111/j.1399-0039.1993.tb02001.x.
  3. ↑ derived from IMGT/HLA
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660. doi:10.1034/j.1399-0039.2003.00062.x. External link in |title= (help)
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