HDLBP

HDLBP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHDLBP, HBP, PRO2900, VGL, high density lipoprotein binding protein
External IDsMGI: 99256 HomoloGene: 38035 GeneCards: HDLBP
Gene location (Human)
Chr.Chromosome 2 (human)[1]
BandNo data availableStart241,227,264 bp[1]
End241,317,061 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

3069

110611

Ensembl

ENSG00000115677

ENSMUSG00000034088

UniProt

Q00341

Q8VDJ3

RefSeq (mRNA)

NM_001301364
NM_133808

RefSeq (protein)

NP_001288293
NP_598569

Location (UCSC)Chr 2: 241.23 – 241.32 MbChr 1: 93.41 – 93.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Vigilin is a protein that in humans is encoded by the HDLBP gene.[5][6][7]

High density lipoprotein-binding protein, also known as vigilin, is a 110-kD protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol.[supplied by OMIM][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000115677 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034088 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. McKnight GL, Reasoner J, Gilbert T, Sundquist KO, Hokland B, McKernan PA, Champagne J, Johnson CJ, Bailey MC, Holly R, et al. (Jul 1992). "Cloning and expression of a cellular high density lipoprotein-binding protein that is up-regulated by cholesterol loading of cells". J Biol Chem. 267 (17): 12131–41. PMID 1318310.
  6. Xia YR, Klisak I, Sparkes RS, Oram J, Lusis AJ (Jul 1993). "Localization of the gene for high-density lipoprotein binding protein (HDLBP) to human chromosome 2q37". Genomics. 16 (2): 524–5. PMID 8390966. doi:10.1006/geno.1993.1221.
  7. 1 2 "Entrez Gene: HDLBP high density lipoprotein binding protein (vigilin)".

Further reading


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