Glycoprotein endo-alpha-1,2-mannosidase
| Glycoprotein endo-alpha-1,2-mannosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.130 | ||||||||
| CAS number | 108022-16-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Glycoprotein endo-alpha-1,2-mannosidase (EC 3.2.1.130, glucosylmannosidase, endo-alpha-D-mannosidase, endo-alpha-mannosidase, endomannosidase, glucosyl mannosidase) is an enzyme with systematic name glycoprotein glucosylmannohydrolase.[1][2] This enzyme catalyses the following chemical reaction
- Hydrolysis of the terminal alpha-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane
This protein is involved in the synthesis of glycoproteins.
See also
References
- ↑ Lubas, W.A.; Spiro, R.G. (1987). "Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme". J. Biol. Chem. 262: 3775–3781. PMID 3818665.
- ↑ Tulsiani, D.R.P.; Coleman, V.P.; Touster, O. (1990). "Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and endomannosidase (glucosyl mannosidase)". Arch. Biochem. Biophys. 277: 114–121. PMID 2407194. doi:10.1016/0003-9861(90)90558-g.
External links
- Glycoprotein endo-alpha-1,2-mannosidase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from
Wikipedia.
The text is licensed under Creative Commons - Attribution - Sharealike.
Additional terms may apply for the media files.