Glutamate—methylamine ligase
| glutamate-methylamine ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 6.3.4.12 | ||||||||
| CAS number | 37318-69-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a glutamate-methylamine ligase (EC 6.3.4.12) is an enzyme that catalyzes the chemical reaction
- ATP + L-glutamate + methylamine ADP + phosphate + N5-methyl-L-glutamine
The 3 substrates of this enzyme are ATP, L-glutamate, and methylamine, whereas its 3 products are ADP, phosphate, and N5-methyl-L-glutamine.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is L-glutamate:methylamine ligase (ADP-forming). This enzyme is also called gamma-glutamylmethylamide synthetase.
References
- Kung HF, Wagner C (1969). "Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine". J. Biol. Chem. 244 (15): 4136–40. PMID 5800436.
This article is issued from
Wikipedia.
The text is licensed under Creative Commons - Attribution - Sharealike.
Additional terms may apply for the media files.