Gamma-glutamyltransferase 6

GGT6
Identifiers
AliasesGGT6, gamma-glutamyltransferase 6
External IDsMGI: 1918772 HomoloGene: 51918 GeneCards: GGT6
EC number3.4.19.13
Orthologs
SpeciesHumanMouse
Entrez

124975

71522

Ensembl

ENSG00000167741

ENSMUSG00000040471

UniProt

Q6P531

Q6PDE7

RefSeq (mRNA)

NM_153338
NM_001122890
NM_001288702
NM_001288703
NM_001288704

NM_027819

RefSeq (protein)

NP_001116362
NP_001275631
NP_001275632
NP_001275633
NP_699169

NP_082095

Location (UCSC)Chr 17: 4.56 – 4.56 MbChr 11: 72.44 – 72.44 Mb
PubMed search[1][2]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-glutamyltransferase 6 is a protein that in humans is encoded by the GGT6 gene. [3]

Function

GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ "Entrez Gene: Gamma-glutamyltransferase 6". Retrieved 2016-03-11.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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