GFRA3

GFRA3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGFRA3, GDNFR3, GDNF family receptor alpha 3
External IDsMGI: 1201403 HomoloGene: 1146 GeneCards: GFRA3
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

2676

14587

Ensembl

ENSG00000146013

ENSMUSG00000024366

UniProt

O60609

O35118

RefSeq (mRNA)

NM_001496

NM_010280

RefSeq (protein)

NP_001487

NP_034410

Location (UCSC)Chr 5: 138.25 – 138.27 MbChr 18: 34.69 – 34.72 Mb
PubMed search[1][2]
Wikidata
View/Edit HumanView/Edit Mouse

GDNF family receptor alpha-3 (GFRα3), also known as the artemin receptor, is a protein that in humans is encoded by the GFRA3 gene.[3][4]

Function

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.[4]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Jing S, Yu Y, Fang M, Hu Z, Holst PL, Boone T, Delaney J, Schultz H, Zhou R, Fox GM (Dec 1997). "GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family". The Journal of Biological Chemistry. 272 (52): 33111–7. PMID 9407096. doi:10.1074/jbc.272.52.33111.
  4. 1 2 "Entrez Gene: GFRA3 GDNF family receptor alpha 3".

Further reading


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