Ileus

Ileus
A gangrenous ileus
Pronunciation
  • /ˈɪliəs/
Classification and external resources
Specialty General surgery
ICD-10 K31.5, K56.0, K56.3, K56.7, P75, P76.1
ICD-9-CM 537.2, 560.1, 560.31, 777.1, 777.4
DiseasesDB 6706
MedlinePlus 000260
eMedicine article/178948
Patient UK Ileus
MeSH D045823

Ileus is a disruption of the normal propulsive ability of the gastrointestinal tract. Although ileus originally referred to any lack of digestive propulsion, including bowel obstruction,[1][2] up-to-date medical usage restricts its meaning to those disruptions caused by the failure of peristalsis, rather than by mechanical obstruction.[3][4] Although certain older terms such as gallstone ileus and meconium ileus persist in usage, they are now misnomers[5] (which does not mean that they are incorrect or obsolete, but rather that they are known to not sound like what they really are).

The word ileus is from Greek εἰλεός eileós, "intestinal obstruction".

Signs and symptoms

Symptoms of ileus include, but are not limited to:

Cause

Decreased propulsive ability may be broadly classified as caused either by bowel obstruction or intestinal atony or paralysis. However, instances with symptoms and signs of a bowel obstruction occur, but with the absence of a mechanical obstruction, mainly in acute colonic pseudo-obstruction, Ogilvie's syndrome.

Bowel obstruction

A bowel obstruction is generally a mechanical obstruction of the gastrointestinal tract.

Intestinal paralysis

Paralysis of the intestine is often termed paralytic ileus, in which the intestinal paralysis need not be complete, but it must be sufficient to prohibit the passage of food through the intestine and lead to intestinal blockage. Paralytic ileus is a common side effect of some types of surgery, commonly called postsurgical ileus. It can also result from certain drugs and from various injuries and illnesses, such as acute pancreatitis. Paralytic ileus causes constipation and bloating. On listening to the abdomen with a stethoscope, no bowel sounds are heard because the bowel is inactive.

A temporary paralysis of a portion of the intestines occurs typically after abdominal surgery. Since the intestinal content of this portion is unable to move forward, food or drink should be avoided until peristaltic sound is heard, by auscultation (use of a stethoscope) of the area where this portion lies. Intestinal atony or paralysis may be caused by inhibitory neural reflexes, inflammation or other implication of neurohumoral peptides.

Risk factors

Treatment

Traditionally, nothing by mouth was considered to be mandatory in all cases, but gentle feeding by enteral feeding tube may help to restore motility by triggering the gut's normal feedback signals, so this is the recommended management initially.[7] When the patient has severe, persistent signs that motility is completely disrupted, nasogastric suction and parenteral nutrition may be required until passage is restored. In such cases, continuing aggressive enteral feeding causes a risk of perforating the gut.

Several options are available in the case of paralytic ileus. Most treatment is supportive. If caused by medication, the offending agent is discontinued or reduced. Bowel movements may be stimulated by prescribing lactulose, erythromycin or, in severe cases that are thought to have a neurological component (such as Ogilvie's syndrome), neostigmine. There is also evidence from a systematic review of randomized controlled trials that chewing gum, as a form of 'sham feeding', may stimulate gastrointestinal motility in the post-operative period and reduce the duration of postoperative ileus.[8]

If possible the underlying cause is corrected (e.g. replace electrolytes).

Other animals

Ileus is a cause of colic in horses due to functional obstruction of the intestines. It most commonly seen in horses postoperatively, especially following colic surgery.[9] Horses experiencing ileus are at risk for gastric rupture due to rapid reflux build-up, and require intense medical management with frequent nasogastric intubation.[9] Ileus may increase adhesion formation, because intestinal segments have more prolonged contact and intestinal distention causes serosal injury and ischemia. It is usually treated with aggressive fluid support, prokinetics, and anti-inflammatories.[9]

References

  1. ↑ thefreedictionary.com > Ileus Citing:
    • Dorland's Medical Dictionary for Health Consumers. 2007
    • The American Heritage Medical Dictionary Copyright 2007
    • Mosby's Medical Dictionary, 8th edition. 2009
    • Saunders Comprehensive Veterinary Dictionary, 3 ed. 2007
  2. ↑ Merriam-Webster's medical dictionary. Retrieved Nov, 9, 2010
  3. ↑ Townsend CM, Beauchamp RD, Evers BM, Mattox KL (2004). "The biological basis of modern surgical practice". Sabiston Textbook of Surgery (17th ed.). Elsevier Saunders.
  4. ↑ Livingston EH, Passaro EP (January 1990). "Postoperative ileus". Dig. Dis. Sci. 35 (1): 121–32. PMID 2403907. doi:10.1007/bf01537233.
  5. ↑ Feldman M, Friedman LS, Brandt LJ, Sleisenger MH (2006). "Intestinal Obstruction and Ileus". Sleisenger & Fordtran's Gastrointestinal and Liver Disease (8th ed.). Elsevier Saunders.
  6. ↑ Kitabchi AE, Umpierrez GE, Murphy MB, et al. (January 2001). "Management of hyperglycemic crises in patients with diabetes". Diabetes Care. 24 (1): 131–53. PMID 11194218. doi:10.2337/diacare.24.1.131.
  7. ↑ McClave SA, Martindale RG, Vanek VW, et al. (2009). "Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)". JPEN J Parenter Enteral Nutr. 33 (3): 277–316. PMID 19398613. doi:10.1177/0148607109335234.
  8. ↑ Fitzgerald JE, Ahmed I (December 2009). "Systematic review and meta-analysis of chewing-gum therapy in the reduction of postoperative paralytic ileus following gastrointestinal surgery". World J Surg. 33 (12): 2557–66. PMID 19763686. doi:10.1007/s00268-009-0104-5.
  9. 1 2 3 Larson, Erica. "Equine Postoperative Ileus Insights". www.thehorse.com. The Horse. Retrieved 4 July 2014.
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