Four boxes test

The four boxes test is a computer-based test used to measure reaction times. In the test, a black circle appears in one of four boxes on the screen, and the patient presses the corresponding key on the keyboard as quickly as possible. The next circle appears after 500 ms, until 52 circles have been exposed. The computer measures the time the subject takes to complete the test and the number of errors they make.^[1]

The test has been used to measure long-term cognitive dysfunction in elderly people who have undergone an operation.^[2] When subjects had undergone anesthesia with different drugs, and were then tested using the Stroop Colour and Word Interference Test, the digit symbol substitution test and the four boxes test, recovery times varied both by anesthetic and by type of test.^[3] Other studies have shown that there is an association between postoperative cognitive dysfunction (POCD) and impaired performance in the four boxes test, but that the test is not a good predictor of POCD.^[4]

References

↑ Houx P; Jolles J. (1993). "Age-related decline of psychomotor speed: effects of age, brain health, sex and education" (PDF). Percept Mot Skills. 76 (1): 195–211. PMID 8451129. doi:10.2466/pms.1993.76.1.195. Retrieved 2010-09-25.
↑ J T Moller; P Cluitmans; L S Rasmussen; P Houx; H Rasmussen; J Canet; P Rabbitt; J Jolles; K Larsen; C D Hanning; O Langeron; T Johnson; P M Lauven; P A Kristensen; A Biedler; H van Beem; O Fraidakis; J H Silverstein; J E W Beneken; J S Gravenstein (March 21, 1998). "Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study". The Lancet. Retrieved 2010-09-25.
↑ Biedler A; Juckenhöfel S; Feisel C; Wilhelm W; Larsen R. (Apr 2000). "Cognitive impairment in the early postoperative period after remifentanil-propofol and sevoflurane-fentanyl anesthesia". Anaesthesist. 49 (4): 286–90. PMID 10840538.
↑ J. STEINMETZ; L. S. RASMUSSEN (January 2008). "Choice reaction time in patients with post-operative cognitive dysfunction†". Acta Anaesthesiologica Scandinavica. 52 (1): 95–98. doi:10.1111/j.1399-6576.2007.01463.x.

Neuropsychological tests
Battery	Cognistat Halstead-Reitan Neuropsychological Battery Luria-Nebraska neuropsychological battery Montreal Cognitive Assessment Repeatable Battery for the Assessment of Neuropsychological Status
Arousal/Attention	Continuous Performance Task d2 Test of Attention Four boxes test Galveston Orientation and Amnesia Test Morningness-eveningness questionnaire Paced Auditory Serial Addition Test Posner cueing task Test of everyday attention Test of Variables of Attention
Sensation/Perception	Bender-Gestalt Test Benton Visual Retention Test Dot cancellation test Judgment of Line Orientation Navon figure Rey-Osterrieth Complex Figure
Memory	1-2-AX working memory task California Verbal Learning Test Corsi block-tapping test Digit symbol substitution test Doors and People MCI Screen Test of Memory Malingering Wechsler Memory Scale
Language	Boston Diagnostic Aphasia Examination Boston Naming Test Comprehensive Aphasia Test Controlled Oral Word Association Test Thurstone Word Fluency Test Token Test
Motor	Compensatory tracking task Purdue Pegboard Test
Problem-solving	Delis–Kaplan Executive Function System Hayling and Brixton tests Tower of London Trail Making Test Wisconsin Card Sorting Test
Sleep	Epworth Sleepiness Scale
Specific impairments	British Columbia Postconcussion Symptom Inventory Clinical Dementia Rating Digit Cancellation Test (Alzheimer's) Disability Rating Scale Florida Cognitive Activities Scale Glasgow Coma Scale Glasgow Outcome Scale Pediatric Attention Disorders Diagnostic Screener Rivermead post-concussion symptoms questionnaire
Intelligence	National Adult Reading Test Wechsler Adult Intelligence Scale Wechsler Intelligence Scale for Children Wechsler Preschool and Primary Scale of Intelligence Wechsler Test of Adult Reading
Bed-side	Abbreviated mental test score Addenbrooke's cognitive examination Brief Cognitive Assessment Tool General Practitioner Assessment Of Cognition Mini–mental state examination
Social	Vineland Social Maturity Scale

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