Flopristin

Flopristin
Names

Other names (16R)-16-Desoxy-16-fluoropristinamycin IIB; RPR 132552; RPR 132552A
Identifiers
CAS Number	318498-76-9^Y
3D model (JSmol)	Interactive image
ECHA InfoCard	100.218.104
UNII	OZV2QPB39M
SMILES O[C@H](/C=C(C)/C=C/CNC(/C=C/[C@@H](C)[C@H](OC1=O)C(C)C)=O)C[C@@H](F)CC2=NC(C(N3[C@@H]1CCC3)=O)=CO2
Properties
Chemical formula	C₂₈H₃₈FN₃O₆
Molar mass	531.63 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Flopristin is a semi-synthetic antibiotic of the streptogramin A class. It is a fluorinated derivative of pristinamycin IIB.

Flopristin is one of the components of the experimental drug NXL103.^[1]

References

↑ Pankuch, Glenn A.; Kelly, Linda M.; Lin, Gengrong; Bryskier, Andre; Couturier, Catherine; Jacobs, Michael R.; Appelbaum, Peter C. (2003). "Activities of a new oral streptogramin, XRP 2868, compared to those of other agents against Streptococcus pneumoniae and Haemophilus species". Antimicrobial Agents and Chemotherapy. 47 (10): 3270–3274. PMC 201162 . PMID 14506040. doi:10.1128/AAC.47.10.3270-3274.2003.

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