Fast Green FCF

Fast Green FCF

Names
IUPAC name ethyl - [4 - [ [4 - [ethyl -[(3 - sulfophenyl) methyl] amino] phenyl] - (4 - hydroxy - 2 - sulfophenyl) methylidene] - 1 - cyclohexa - 2, 5 - dienylidene] - [(3 - sulfophenyl) methyl] azanium
Other names Food green 3, FD&C Green No. 3, Green 1724, Solid Green FCF, and C.I. 42053
Identifiers
CAS Number	2353-45-9 Y
3D model (JSmol)	Interactive image
ChemSpider	16002 Y
ECHA InfoCard	100.017.356
E number	E143 (colours)
KEGG	C19423 N
PubChem CID	16888
UNII	9J3VQ0Y6BV N
InChI InChI=1S/C37H36N2O10S3.2Na/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46;;/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49);;/q;2*+1/p-2 Y Key: RZSYLLSAWYUBPE-UHFFFAOYSA-L Y InChI=1/C37H36N2O10S3.2Na/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46;;/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49);;/q;2*+1/p-2 Key: RZSYLLSAWYUBPE-NUQVWONBAL
SMILES [Na+].[Na+].[O-]S(=O)(=O)c1cccc(c1)CN(c2ccc(cc2)\C(=C\4/C=C\C(=[N+](\CC)Cc3cccc(c3)S([O-])(=O)=O)/C=C/4)c5ccc(O)cc5S([O-])(=O)=O)CC
Properties
Chemical formula	C37H37N2O10S3+
Molar mass	765.89 g/mol
Hazards
R-phrases (outdated)	R36 R37 R38
NFPA 704	1 2 0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Fast Green FCF, also called Food green 3, FD&C Green No. 3, Green 1724, Solid Green FCF, and C.I. 42053, is a sea green triarylmethane food dye. Its E number is E143.

Fast Green FCF is recommended as a replacement of Light Green SF yellowish in Masson's trichrome, as its color is more brilliant and less likely to fade. It is used as a quantitative stain for histones at alkaline pH after acid extraction of DNA. It is also used as a protein stain in electrophoresis. Its absorption maximum is at 625 nm.

Fast Green FCF is poorly absorbed by the intestines.^[1] Its use as a food dye is prohibited in European Union and some other countries. It can be used for tinned green peas and other vegetables, jellies, sauces, fish, desserts, and dry bakery mixes at level of up to 100 mg/kg.^[2] In the United States, Fast Green FCF is the least used of the seven main FDA approved dyes.

Toxicology

This substance has been found to have tumorigenic effects in experimental animals, as well as mutagenic effects in both experimental animals and humans. It furthermore risks irritation of eyes, skin, digestive tract, and respiratory tract in its undiluted form.^[3]

Notes