FUB-APINACA

FUB-APINACA
Legal status
Legal status
Identifiers
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C25H26FN3O
Molar mass 403.5 g/mol
3D model (JSmol)

FUB-APINACA (also known as FUB-AKB48) is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1] It is an analogue of APINACA and 5F-APINACA where the pentyl chain has been replaced with fluorobenzyl.

Pharmacology

FUB-AKB-48 acts as a full agonist with a binding affinity of 1.06nM at CB1 and 0.174nM at CB2 cannabinoid receptors.[2]

Sweden's public health agency suggested classifying FUB-APINACA as a hazardous substance on November 10, 2014.[3]

It is also illegal in Alabama (listed as FUB-AKB48).[4]

See also

References

  1. "FUB-AKB48". Cayman Chemical. Retrieved 23 July 2015.
  2. Hess, Cornelius; Schoeder, ClaraT.; Pillaiyar, Thanigaimalai; Madea, Burkhard; Müller, ChristaE. (1 July 2016). "Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice". Forensic Toxicology. 34 (2): 329–343. ISSN 1860-8965. PMC 4929166Freely accessible. PMID 27429655. doi:10.1007/s11419-016-0320-2.
  3. "Cannabinoider föreslås bli klassade som hälsofarlig vara". Folkhälsomyndigheten. Retrieved 23 July 2015.
  4. Alabama Senate Bill SB 333: Controlled Substances


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