FCHO1

FCHO1

Identifiers

FCHO1, FCH domain only 1

External IDs

MGI: 1921265 HomoloGene: 22869 GeneCards: FCHO1

Gene ontology
Molecular function	• AP-2 adaptor complex binding • protein binding
Cellular component	• plasma membrane • clathrin-coated pit • membrane • clathrin-coated vesicle • nucleoplasm • cytosol
Biological process	• clathrin-dependent endocytosis • endocytosis • clathrin coat assembly • membrane organization
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


23149


74015


ENSG00000130475


ENSMUSG00000070000


O14526


Q8K285

RefSeq (mRNA)


NM_001161357 NM_001161358 NM_001161359 NM_015122


NM_028715

RefSeq (protein)


NP_001154829 NP_001154830 NP_001154831 NP_055937


NP_082991

Location (UCSC)

Chr 19: 17.75 – 17.79 Mb

Chr 8: 71.71 – 71.73 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

FCH domain only 1 is a protein that in humans is encoded by the FCHO1 gene. ^[3]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: FCH domain only 1". Retrieved 2017-05-13.

Further reading

Sakaushi S, Inoue K, Zushi H, Senda-Murata K, Fukada T, Oka S, Sugimoto K (2007). "Dynamic behavior of FCHO1 revealed by live-cell imaging microscopy: its possible involvement in clathrin-coated vesicle formation". Biosci. Biotechnol. Biochem. 71 (7): 1764–8. PMID 17617719. doi:10.1271/bbb.60720.
Henne WM, Boucrot E, Meinecke M, Evergren E, Vallis Y, Mittal R, McMahon HT (2010). "FCHo proteins are nucleators of clathrin-mediated endocytosis". Science. 328 (5983): 1281–4. PMC 2883440 . PMID 20448150. doi:10.1126/science.1188462.
Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM (2012). "Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning". Nat. Cell Biol. 14 (5): 488–501. PMC 3354769 . PMID 22484487. doi:10.1038/ncb2473.

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