FBXO11

FBXO11
Identifiers
Aliases	FBXO11, FBX11, PRMT9, UBR6, VIT1, UG063H01, F-box protein 11
External IDs	MGI: 2147134 HomoloGene: 11843 GeneCards: FBXO11
Gene ontology Molecular function • zinc ion binding • protein binding • protein-arginine N-methyltransferase activity • metal ion binding • ubiquitin-protein transferase activity Cellular component • ubiquitin ligase complex • cytoplasm • nucleolus • nucleus • chromosome • cytosol Biological process • cellular protein modification process • sensory perception of sound • protein ubiquitination • ubiquitin-dependent protein catabolic process • peptidyl-arginine N-methylation • protein polyubiquitination • post-translational protein modification Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	80204	225055
Ensembl	ENSG00000138081	ENSMUSG00000005371
UniProt	Q86XK2	Q7TPD1
RefSeq (mRNA)	NM_001190274 NM_012167 NM_018693 NM_025133	NM_001081034 NM_001348248
RefSeq (protein)	NP_001177203 NP_079409	NP_001074503 NP_001335177
Location (UCSC)	Chr 2: 47.79 – 47.91 Mb	Chr 17: 87.99 – 88.07 Mb
PubMed search	[1]	[2]
Wikidata
View/Edit Human View/Edit Mouse

F-box only protein 11 is a protein that in humans is encoded by the FBXO11 gene.^[3][4][5][6]

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.^[6]

References

Further reading