FBRS

FBRS

Identifiers

FBRS, FBS, FBS1, fibrosin

External IDs

MGI: 104648 HomoloGene: 79554 GeneCards: FBRS

Gene ontology
Molecular function	• growth factor activity
Cellular component	• extracellular space
Biological process	• positive regulation of fibroblast proliferation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


64319


14123


ENSG00000156860


ENSMUSG00000042423


Q9HAH7


Q8R089

RefSeq (mRNA)


NM_001105079 NM_022452


NM_010183

RefSeq (protein)


NP_001098549


NP_034313

Location (UCSC)

Chr 16: 30.66 – 30.67 Mb

Chr 7: 127.48 – 127.49 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Probable fibrosin-1 long transcript protein is a protein that in humans is encoded by the FBRS gene.^[3]^[4]^[5]

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation (Prakash and Robbins, 1998).[supplied by OMIM]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Prakash S, Robbins PW, Wyler DJ (Apr 1995). "Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin". Proc Natl Acad Sci U S A. 92 (6): 2154–8. PMC 42442 . PMID 7892239. doi:10.1073/pnas.92.6.2154.
↑ Prakash S, Robbins PW (Nov 1998). "Cloning and analysis of the cDNA for human fibrosin, a novel fibrogenic lymphokine". DNA Cell Biol. 17 (10): 879–84. PMID 9809749. doi:10.1089/dna.1998.17.879.
1 2 "Entrez Gene: FBS1 fibrosin 1".

Further reading

Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549. doi:10.1101/gr.6.9.807.
Prakash S, Nanji AA, Robbins PW (1999). "Fibrosin: A novel lymphokine in alcohol-induced fibrosis". Exp. Mol. Pathol. 67 (1): 40–9. PMID 10493891. doi:10.1006/exmp.1999.2274.
Prakash S, Robbins PW (2002). "Fibrosin: a novel lymphokine in wound healing". Exp. Mol. Pathol. 71 (3): 247–55. PMID 11733950. doi:10.1006/exmp.2001.2402.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406.
Prakash S, Paul WE, Robbins PW (2007). "Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts". Exp. Mol. Pathol. 82 (1): 42–8. PMID 17083929. doi:10.1016/j.yexmp.2006.06.008.

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