Evogliptin

Evogliptin
Clinical data

Routes of administration	By mouth
ATC code	None
Identifiers
IUPAC name (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-{[(2-methyl-2-propanyl)oxy]methyl}-2-piperazinone
CAS Number	1222102-29-5
PubChem CID	25022354
ChemSpider	26339341
UNII	09118300L7
ChEMBL	CHEMBL1779710
Chemical and physical data
Formula	C₁₉H₂₆F₃N₃O₃
Molar mass	401.43 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)(C)OC[C@@H]1C(=O)NCCN1C(=O)C[C@@H](Cc2cc(c(cc2F)F)F)N
InChI InChI=1S/C19H26F3N3O3/c1-19(2,3)28-10-16-18(27)24-4-5-25(16)17(26)8-12(23)6-11-7-14(21)15(22)9-13(11)20/h7,9,12,16H,4-6,8,10,23H2,1-3H3,(H,24,27)/t12-,16-/m1/s1 Key:LCDDAGSJHKEABN-MLGOLLRUSA-N

Evogliptin (INN; trade name Suganon, previously identified as DA-1229) is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor or "gliptin" class of drugs.^[1] It was developed by the South Korean pharmaceutical company Dong-A ST and is approved for use in South Korea.^[2]

References

↑ McCormack PL. (2015). "Evogliptin: First Global Approval.". Drugs. 75 (17): 2045–2049. PMID 26541763. doi:10.1007/s40265-015-0496-5.
↑ "Dong-A ST’s DPP4 inhibitor, SUGANON, got approved for type 2 diabetes in Korea". pipelinereview.com. October 2, 2015.

Oral anti-diabetic drugs, insulins and insulin analogs, and other drugs used in diabetes (A10)

Biguanides	Buformin^‡ Metformin^# Phenformin^‡
TZDs/"glitazones" (PPAR)	Ciglitazone^§ Darglitazone^§ Englitazone^§ Lobeglitazone Netoglitazone^§ Pioglitazone Rivoglitazone^† Rosiglitazone Troglitazone^‡
Dual PPAR agonists	Aleglitazar^† Muraglitazar^§ Saroglitazar Tesaglitazar^§

Sulfonylureas	1st generation: Acetohexamide Carbutamide Chlorpropamide Glycyclamide Metahexamide Tolazamide Tolbutamide 2nd generation: Glibenclamide (glyburide) Glibornuride Glicaramide Gliclazide^# Glimepiride Glipizide Gliquidone Glisoxepide Glyclopyramide
Meglitinides/"glinides"	Mitiglinide Nateglinide Repaglinide

Analogs/other insulins

Other

Aldose reductase inhibitors	Epalrestat Fidarestat^§ Ranirestat^† Tolrestat^‡ Zenarestat^§
Alpha-glucosidase inhibitors	Acarbose Miglitol Voglibose
Amylin analog	Pramlintide
Sodium glucose transporter (SGLT2) inhibitors/"gliflozins"	Canagliflozin Dapagliflozin Empagliflozin Ipragliflozin Remogliflozin^§ Sergliflozin^§ Tofogliflozin^†
Other	Benfluorex^‡ Bromocriptine

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