Eight-cell stage

The eight-cell stage is a period in embryonic development when the conceptus has undergone three cleavages from a single cell, resulting in eight cells. In some mammals, it is at this stage of development that the individual cells begin to adhere tightly, a process called compaction.[1] A single cell can be removed from a pre-compaction 8 cell embryo and used for genetic testing.[2]

References

  1. ↑ Nikas G, Ao A, Winston RM, Handyside AH (July 1996). "Compaction and surface polarity in the human embryo in vitro" (pdf). Biol. Reprod. 55 (1): 32–7. PMID 8793055. doi:10.1095/biolreprod55.1.32.
  2. ↑ "Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridization". Hum. Reprod. Update. 11 (1): 33–41. 2005. PMID 15569702. doi:10.1093/humupd/dmh050.


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