ESD (gene)

ESD

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
3FCX

Identifiers

Aliases

ESD, FGH, esterase D

External IDs

MGI: 3781082 HomoloGene: 55623 GeneCards: ESD

Gene ontology
Molecular function	• S-formylglutathione hydrolase activity • methylumbelliferyl-acetate deacetylase activity • carboxylic ester hydrolase activity • protein binding • hydrolase activity • hydrolase activity, acting on ester bonds • identical protein binding
Cellular component	• cytoplasm • extracellular exosome • endoplasmic reticulum lumen • cytoplasmic vesicle
Biological process	• formaldehyde catabolic process • glutathione derivative biosynthetic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


2098


100040682

Ensembl


ENSG00000139684


n/a

UniProt


P10768


n/a

RefSeq (mRNA)


NM_001984


n/a

RefSeq (protein)


NP_001975


n/a

Location (UCSC)

Chr 13: 46.77 – 46.8 Mb

n/a

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

S-formylglutathione hydrolase is an enzyme that in humans is encoded by the ESD gene.^[3]

References

Munier F, Balmer A, von Moos C, et al. (1991). "[Lausanne study of retinoblastoma, 1986-90: deletion of esterase D locus in a collective of 128 patients]". Klinische Monatsblätter für Augenheilkunde. 198 (5): 419–24. PMID 1886375. doi:10.1055/s-2008-1045999.
Young LJ, Lee EY, To HA, et al. (1988). "Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma.". Hum. Genet. 79 (2): 137–41. PMID 3164702. doi:10.1007/BF00280552.
Lee EY, Lee WH (1986). "Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma.". Proc. Natl. Acad. Sci. U.S.A. 83 (17): 6337–41. PMC 386498 . PMID 3462698. doi:10.1073/pnas.83.17.6337.
Squire J, Dryja TP, Dunn J, et al. (1986). "Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13.". Proc. Natl. Acad. Sci. U.S.A. 83 (17): 6573–7. PMC 386546 . PMID 3462714. doi:10.1073/pnas.83.17.6573.
Lee WH, Wheatley W, Benedict WF, et al. (1986). "Purification, biochemical characterization, and biological function of human esterase D.". Proc. Natl. Acad. Sci. U.S.A. 83 (18): 6790–4. PMC 386595 . PMID 3462728. doi:10.1073/pnas.83.18.6790.
Cortivo P, Caenazzo L, Crestani C, et al. (1987). "Genetic study of red cell esterase D polymorphism by ultrathin layer isoelectric focusing. Distribution in the Veneto population (Italy).". Z. Rechtsmed. 98 (1): 39–42. PMID 3591015. doi:10.1007/BF00200384.
Eiberg H, Mohr J (1986). "Identity of the polymorphisms for esterase D and S-formylglutathione hydrolase in red blood cells.". Hum. Genet. 74 (2): 174–5. PMID 3770744. doi:10.1007/BF00282085.
Tsuchida S, Fukui E, Ikemoto S (1994). "Molecular analysis of esterase D polymorphism.". Hum. Genet. 93 (3): 255–8. PMID 7907313. doi:10.1007/BF00212018.
Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. PMC 16901 . PMID 10931946. doi:10.1073/pnas.160270997.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Saito S, Iida A, Sekine A, et al. (2003). "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.". J. Hum. Genet. 48 (5): 249–70. PMID 12721789. doi:10.1007/s10038-003-0021-7.
Sergeev AS, Agapova RK, Bogadel'nikova IV, Perel'man MI (2003). "[The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]". Genetika. 39 (7): 996–1002. PMID 12942785.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature. 428 (6982): 522–8. PMC 2665288 . PMID 15057823. doi:10.1038/nature02379.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.

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ESD (gene)

References

Further reading