EBNA1BP2

EBNA1BP2

Identifiers

EBNA1BP2, EBP2, NOBP, P40, EBNA1 binding protein 2

External IDs

MGI: 1916322 HomoloGene: 4969 GeneCards: EBNA1BP2

Gene ontology
Molecular function	• RNA binding • protein binding
Cellular component	• nucleus • nuclear periphery • preribosome, large subunit precursor • nucleolus
Biological process	• ribosome biogenesis • ribosomal large subunit biogenesis • rRNA processing
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


10969


69072


ENSG00000117395


ENSMUSG00000028729


Q99848 Q6IB29


Q9D903

RefSeq (mRNA)


NM_006824 NM_001159936


NM_026932

RefSeq (protein)


NP_001153408 NP_006815 NP_006815.2


NP_081208

Location (UCSC)

Chr 1: 43.16 – 43.27 Mb

Chr 4: 118.62 – 118.63 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Probable rRNA-processing protein EBP2 is a protein that in humans is encoded by the EBNA1BP2 gene.^[3]^[4]^[5]

Interactions

EBNA1BP2 has been shown to interact with FGF3.^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Shire K, Ceccarelli DF, Avolio-Hunter TM, Frappier L (May 1999). "EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance". J Virol. 73 (4): 2587–95. PMC 104013 . PMID 10074103.
1 2 Reimers K, Antoine M, Zapatka M, Blecken V, Dickson C, Kiefer P (Jul 2001). "NoBP, a nuclear fibroblast growth factor 3 binding protein, is cell cycle regulated and promotes cell growth". Mol Cell Biol. 21 (15): 4996–5007. PMC 87226 . PMID 11438656. doi:10.1128/MCB.21.15.4996-5007.2001.
↑ "Entrez Gene: EBNA1BP2 EBNA1 binding protein 2".

Further reading

Chatterjee A, Freeman JW, Busch H (1987). "Identification and partial characterization of a Mr 40,000 nucleolar antigen associated with cell proliferation.". Cancer Res. 47 (4): 1123–9. PMID 2879624.
Sherrington R, Rogaev EI, Liang Y, et al. (1995). "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.". Nature. 375 (6534): 754–60. PMID 7596406. doi:10.1038/375754a0.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3.
Huber MD, Dworet JH, Shire K, et al. (2000). "The budding yeast homolog of the human EBNA1-binding protein 2 (Ebp2p) is an essential nucleolar protein required for pre-rRNA processing". J. Biol. Chem. 275 (37): 28764–73. PMID 10849420. doi:10.1074/jbc.M000594200.
Henning D, Valdez BC (2001). "Expression of p40/Epstein-Barr virus nuclear antigen 1 binding protein 2". Biochem. Biophys. Res. Commun. 283 (2): 430–6. PMID 11327720. doi:10.1006/bbrc.2001.4780.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. PMID 11790298. doi:10.1016/S0960-9822(01)00650-9.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Kapoor P, Frappier L (2003). "EBNA1 partitions Epstein-Barr virus plasmids in yeast cells by attaching to human EBNA1-binding protein 2 on mitotic chromosomes". J. Virol. 77 (12): 6946–56. PMC 156160 . PMID 12768013. doi:10.1128/JVI.77.12.6946-6956.2003.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Kapoor P, Lavoie BD, Frappier L (2005). "EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases". Mol. Cell. Biol. 25 (12): 4934–45. PMC 1140579 . PMID 15923612. doi:10.1128/MCB.25.12.4934-4945.2005.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. PMC 1847948 . PMID 17353931. doi:10.1038/msb4100134.

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