Domenico de Simone
| Styles of Tommaso Pasquale Gizzi | |
|---|---|
 | |
| Reference style | His Eminence |
| Spoken style | Your Eminence |
| Informal style | Cardinal |
| See | Prefect of Papal Household |
Domenico de Simone (29 November 1768–9 November 1837) was an Italian cardinal. He was part of the Roman Curia.
He was born in Benevento and died in Rome.
He was made a cardinal in March 1830 by Pope Pius VIII and took part in the 1830–1831 conclave which chose Pope Gregory XVI.
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