Dinitrophenyl

Dinitrophenyl is a chemical compound containing nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation.[1][2] Dinitrophenyl does not elicit any immune response on its own and it does not bind to any antigen.[3]

References

  1. ↑ Berd, D; Maguire Jr, H. C.; Mastrangelo, M. J.; Murphy, G (1994). "Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine". Cancer immunology, immunotherapy : CII. 39 (3): 141–7. PMID 7923243. doi:10.1007/s002620050105.
  2. ↑ Manne, J; Mastrangelo, M. J.; Sato, T; Berd, D (2002). "TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine". Journal of immunology (Baltimore, Md. : 1950). 169 (6): 3407–12. PMID 12218163. doi:10.4049/jimmunol.169.6.3407.
  3. ↑ "Dinitrophenyl". NCI Drug Dictionary. National Cancer Institute.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.