Deoxyribonucleoprotein

Nucleosome=DNA + histones: Crystal structure[1]). Histones H2A, H2B, H3 and H4 are proper colored, DNA is gray.
Nucleosome: DNA + histone configuration

Deoxyribonucleoprotein (DNP) is the complex of DNA and protein[2] in which DNA is usually found upon cell disruption and isolation.[3][4]

The most widespread deoxyribonucleoproteins are nucleosomes, in which the component is nuclear DNA. The proteins combined with DNA are histones and protamines; the resulting nucleoproteins are located in chromosomes. Thus, the entire chromosome, i.e. chromatin in eukaryotes consists of such nucleoproteins.[5][6]

Many viruses are little more than an organized collection of deoxyribonucleoproteins.

See also

References

  1. RasTop (Molecular Visualization Software).
  2. Deoxyribonucleoproteins at the US National Library of Medicine Medical Subject Headings (MeSH)
  3. http://cancerweb.ncl.ac.uk/cgi-bin/omd?Deoxyribonucleoprotein
  4. "deoxyribonucleoprotein (DNP, Dnp)".
  5. Graeme K. Hunter G. K. (2000): Vital Forces. The discovery of the molecular basis of life. Academic Press, London 2000, ISBN 0-12-361811-8.
  6. Nelson D. L., Michael M. Cox M. M. (2013): Lehninger Principles of Biochemistry. W. H. Freeman, ISBN 978-1-4641-0962-1.


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