Deoxyribonuclease IV
| Deoxyribonuclease IV (phage-T4-induced) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.21.2 | ||||||||
| CAS number | 63363-78-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Deoxyribonuclease IV (phage-T4-induced) (EC 3.1.21.2, endodeoxyribonuclease IV (phage T4-induced), E. coli endonuclease IV, endodeoxyribonuclease, redoxyendonuclease, deoxriboendonuclease, Escherichia coli endonuclease II, endonuclease II, DNA-adenine-transferase) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products
Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.
References
- ↑ Friedberg, E.C.; Goldthwait, D.A. (1969). "Endonuclease II of E. coli. I. Isolation and purification". Proc. Natl. Acad. Sci. USA. 62 (3): 934–940. PMC 223688
. PMID 4895219. doi:10.1073/pnas.62.3.934. - ↑ Friedberg, E.C.; Hadi, S.-M.; Goldthwait, D.A. (1969). "Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid". J. Biol. Chem. 244 (21): 5879–5889. PMID 4981786.
- ↑ Hadi, S.M.; Goldthwait, D.A. (1971). "Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid". Biochemistry. 10 (26): 4986–4993. PMID 4944066. doi:10.1021/bi00802a024.
- ↑ Sadowski, P.D.; Hurwitz, J. (1969). "Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli". J. Biol. Chem. 244 (22): 6182–6191. PMID 4310836.
See also
External links
- Deoxyriboendonuclease IV at the US National Library of Medicine Medical Subject Headings (MeSH)
- Lindahl T, Gally JA, Edelman GM (1969). "Deoxyribonuclease IV: a new exonuclease from mammalian tissues". Proc. Natl. Acad. Sci. U.S.A. 62 (2): 597–603. PMC 277851 . PMID 5256235. doi:10.1073/pnas.62.2.597.
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