David Sheffield Bell

David Sheffield Bell is an American physician who has researched extensively on the clinical aspects of chronic fatigue syndrome (CFS). He has also conducted evaluations and research in pediatric CFS and written numerous articles about the condition.^[1][2]

Bell is retired^[3] from a private practice in general medicine in the town of Lyndonville, New York which he had started in 1979.^[4] Bell also served as Clinical Associate Professor of Pediatrics at the State University of New York at Buffalo, in Buffalo, New York.^[5]

Training

Bell is a graduate of Harvard University, class of 1967, with an AB degree in English Literature. He graduated in 1971 from Boston University with an MD degree, and in 1976 completed post-doctoral training in pediatrics including Pediatric Behavior and Developmental Disorders.^[6][7]

Work on chronic fatigue syndrome

Bell's interest in CFS began in 1985 when an apparent cluster outbreak of 216 persons occurred in his rural community in upstate New York. He has written extensively on the condition, including a thirteen-year follow-up study of the children who became ill during the original outbreak.^[2][8]

Bell was involved in identifying the outbreak in Lyndonville, New York, of what was known at the time as chronic Epstein-Barr virus (now more commonly referred to as chronic fatigue syndrome or CFS).^[4] When Bell was interviewed about the outbreak in a 1996 Prime Time Live episode, the reporter described Bell's appeal to the Centers for Disease Control and Prevention (CDC) for help with the illness, but Bell says the CDC didn't mention a similar outbreak in Lake Tahoe, which he learned about later. He met with other CFS researchers at a 1987 conference, and joined an investigation with researchers Paul Cheney and Elaine DeFreitas involving a possible retrovirus association with chronic fatigue syndrome.^[9] In 1990, the researchers presented evidence they found DNA sequences very similar to a known human retrovirus in some CFS patients, at a conference in Kyoto, Japan.^[10][11] Their study was later published in the Proceedings of the National Academy of Sciences.^[12] A reporter on Prime Time Live stated the announcement made headlines all over the world. The CDC first ignored their findings,^[9] then later conducted a study and published a paper that refuted the hypothesis.^[13]

Bell wrote The Doctor's Guide to Chronic Fatigue Syndrome, which was published in 1995. The book, which also refers to CFS as "chronic fatigue/immune dysfunction syndrome," or CFIDS, describes Bell's CFIDS disability scale.^[14] Various publications have used or proposed Bell's scale which is similar to the Karnofsky scale, for the documentation of severity of symptoms in chronic fatigue syndrome.^{[15][16][17][18]}

In the 2000 CFS documentary, I Remember Me, Bell appeared in an interview recounting his experiences during the Lyndonville outbreak.^[19][20]

In 2003, Secretary of Health and Human Services Tommy G. Thompson designated Bell chairperson of the Chronic Fatigue Syndrome Advisory Committee (CFSAC), a panel of 11 experts that provides advice and recommendations to the Secretary of Health and Human Services "on the development and implementation of programs to inform the public; health care professionals; and the biomedical, academic, and research communities about advances related to CFS."^[1][21][22]

Bell also served as a board member of the International Association for Chronic Fatigue Syndrome/ME (IACFS/ME),^[23] a professional organization of about 300 members that advocates for the concerns of CFS researchers and clinicians around the world.^[24]

Bell has retired from private practice, but in 2011 was still doing research on the cause of the illness of CFS patients in Lyndonville NY.^[3]

Selected publications

Books

• CFIDS: A Disease of a Thousand Names. D.Pollard, (1988)
• The Doctor's Guide To Chronic Fatigue Syndrome: Understanding, Treating, And Living With Cfids, Da Capo Press (January 17, 1995) ISBN 978-0-201-40797-6
• Curing Fatigue, Berkley (September 1, 1996), ISBN 978-0-425-14983-6
• A Parent's Guide to Cfids: How to Be an Advocate for Your Child With Chronic Fatigue Immune Dysfunction, Informa HealthCare; (March 8, 1999), ISBN 978-0-7890-0631-8
• Faces of CFS, MZR Publishing (August 30, 2000), ISBN 0-9707702-0-0
• Cellular Hypoxia and Neuro-Immune Fatigue, WingSpan Press (July 10, 2007), ISBN 978-1-59594-179-4

Selected Articles

• Leonard A. Jason; Nicole Porter; Elizabeth Shelleby; David S. Bell; Charles W. Lapp; Kathy Rowe & Kenny De Meirleir (November 2008). "A Case Definition for Children with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Clinical Medicine: Pediatrics. 2008 (1): 53–57. 
• Be sure to distinguish CFS from depression, Clinical Psychiatry News, April 1, 2005, Volume: 33 Issue: 4 Page: 14(1)
• Stewart CC, Cookfair DL, Hovey KM, Wende KE, Bell DS, Warner CL (May 2003). "Predictive immunophenotypes: disease-related profile in chronic fatigue syndrome". Cytometry Part B. 53 (1): 26–33. PMID 12717688. doi:10.1002/cyto.b.10034. 
• Gerrity TR, Bates J, Bell DS, et al. (2002). "Chronic fatigue syndrome: what role does the autonomic nervous system play in the pathophysiology of this complex illness?". Neuroimmunomodulation. 10 (3): 134–41. PMID 12481153. doi:10.1159/000067176. 
• Ash-Bernal R, Wall C, Komaroff AL, et al. (January 1995). "Vestibular function test anomalies in patients with chronic fatigue syndrome". Acta Otolaryngol. 115 (1): 9–17. PMID 7762393. doi:10.3109/00016489509133339. 
• Bell DS, Bell KM, Cheney PR (January 1994). "Primary juvenile fibromyalgia syndrome and chronic fatigue syndrome in adolescents". Clin. Infect. Dis. 18 Suppl 1: S21–3. PMID 8148447. doi:10.1093/clinids/18.supplement_1.s21. 
• Bell KM, Cookfair D, Bell DS, Reese P, Cooper L (1991). "Risk factors associated with chronic fatigue syndrome in a cluster of pediatric cases". Rev. Infect. Dis. 13 Suppl 1: S32–8. PMID 2020801. doi:10.1093/clinids/13.supplement_1.s32. 
• Bell DS, Jordan K, Robinson M (May 2001). "Thirteen-year follow-up of children and adolescents with chronic fatigue syndrome". Pediatrics. 107 (5): 994–8. PMID 11331676. doi:10.1542/peds.107.5.994. 
• DeFreitas E, Hilliard B, Cheney PR, et al. (April 1991). "Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome". Proc. Natl. Acad. Sci. U.S.A. 88 (7): 2922–6. PMC 51352 . PMID 1672770. doi:10.1073/pnas.88.7.2922. 
• Streeten DH, Thomas D, Bell DS (July 2000). "The roles of orthostatic hypotension, orthostatic tachycardia, and subnormal erythrocyte volume in the pathogenesis of the chronic fatigue syndrome". Am. J. Med. Sci. 320 (1): 1–8. PMID 10910366. doi:10.1097/00000441-200007000-00001. 

References